High HIV Testing Among Black/Latino Men Who Have Sex with Men Assigned to HIV Self-Testing in a National Randomized Controlled Trial.

IF 2.9 3区 医学 Q3 IMMUNOLOGY
John Guigayoma, Katie Biello, Sara J Becker, Erik Ocean, Lori Ward, Philip A Chan, Jeffrey Klausner, Tyler Wray
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Abstract

Background: Black/Latino men who have sex with men (MSM) in the United States have high rates of undiagnosed HIV infection. To assess whether HIV self-testing increases HIV screening among Black/Latino MSM and how HIV self-testing for Black/Latino MSM compares to White MSM, we analyzed data from a 12-month randomized controlled trial.

Methods: Participants were randomized to quarterly allocation of: HIV testing reminders (control, no HIV self-tests), home delivery of rapid HIV self-tests (standard HIV self-test), or home delivery with counseling 24 hours after opening tests (eTest). In this secondary analysis, we used Poisson regression models to evaluate HIV testing rates for the different approaches among Black/Latino MSM compared to White MSM.

Results: Of a final analytical sample of 713 participants, 353 were White MSM and 360 were Black/Latino MSM. In all approaches, we found no evidence of differences in HIV testing between White MSM and Black/Latino MSM. Predicted probabilities indicated higher testing among Black/Latino MSM assigned to the HIV self-test conditions compared to Black/Latino MSM in the control condition. The probabilities of any HIV testing among Black/Latino MSM in the standard HIV self-test, eTest, and control conditions were 92%, 90%, and 58%, respectively (all p<.05).

Conclusions: Results from this randomized controlled trial suggest that Black/Latino MSM use HIV self-tests at high rates and found no evidence that HIV self-test use differs between Black/Latino MSM and White MSM. Implementation science research is needed to increase the availability of HIV self-tests for all MSM, especially underserved populations such as Black/Latino MSM.

在一项全国随机对照试验中,黑人/拉丁裔男男性行为者中HIV检测率高。
背景:在美国,与男性发生性行为的黑人/拉丁裔男性(MSM)有很高的未确诊艾滋病毒感染率。为了评估艾滋病毒自我检测是否增加了黑人/拉丁裔男同性恋者的艾滋病毒筛查,以及黑人/拉丁裔男同性恋者的艾滋病毒自我检测与白人男同性恋者的比较,我们分析了一项为期12个月的随机对照试验的数据。方法:参与者随机分为:HIV检测提醒组(对照组,无HIV自检组)、HIV快速自检组(标准HIV自检组)、开启检测后24小时上门咨询组(ettest组)。在这一次要分析中,我们使用泊松回归模型来评估黑人/拉丁裔男同性恋者与白人男同性恋者不同方法的HIV检测率。结果:在713名参与者的最终分析样本中,353名是白人MSM, 360名是黑人/拉丁裔MSM。在所有方法中,我们都没有发现白人男男性接触者和黑人/拉丁裔男男性接触者在HIV检测方面存在差异的证据。预测概率表明,与控制条件下的黑人/拉丁裔男男性行为者相比,分配给HIV自检条件的黑人/拉丁裔男男性行为者的检测率更高。黑人/拉丁裔男男性行为者在标准艾滋病毒自检、测试和对照条件下进行艾滋病毒检测的概率分别为92%、90%和58%。结论:该随机对照试验的结果表明,黑人/拉丁裔男男性行为者使用艾滋病毒自检的比例很高,没有证据表明黑人/拉丁裔男男性行为者和白人男男性行为者使用艾滋病毒自检的比例有差异。需要开展实施科学研究,以提高所有男男性行为者,特别是黑人/拉丁裔男男性行为者等服务不足人群的艾滋病毒自我检测的可获得性。
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来源期刊
CiteScore
5.80
自引率
5.60%
发文量
490
审稿时长
3-6 weeks
期刊介绍: JAIDS: Journal of Acquired Immune Deficiency Syndromes​ seeks to end the HIV epidemic by presenting important new science across all disciplines that advance our understanding of the biology, treatment and prevention of HIV infection worldwide. JAIDS: Journal of Acquired Immune Deficiency Syndromes is the trusted, interdisciplinary resource for HIV- and AIDS-related information with a strong focus on basic and translational science, clinical science, and epidemiology and prevention. Co-edited by the foremost leaders in clinical virology, molecular biology, and epidemiology, JAIDS publishes vital information on the advances in diagnosis and treatment of HIV infections, as well as the latest research in the development of therapeutics and vaccine approaches. This ground-breaking journal brings together rigorously peer-reviewed articles, reviews of current research, results of clinical trials, and epidemiologic reports from around the world.
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