Prevalence of Self-Reported Adverse Effects to Cannabis by Older Canadians: A Cross-Sectional Analysis.

IF 3.4 3区医学 Q2 GERIATRICS & GERONTOLOGY

Drugs & Aging Pub Date : 2025-04-23 DOI:10.1007/s40266-025-01206-4

Jennifer Bolt, Kristine Lin, Melanie Fenton, Jennifer M Jakobi

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引用次数: 0

Abstract

Background and objective: Despite the increasing use of cannabis by older Canadians, little is known about cannabis safety in this population, particularly in non-clinical settings. The purpose of this study was to describe the self-reported adverse effects experienced by community-dwelling older Canadians who use cannabis.

Methods: Canadians aged 50 years and older completed an online survey regarding their knowledge, perceptions, and experiences with cannabis. Respondents who reported current cannabis use were asked to report any adverse effects experienced in the past year related to their cannabis use. Adverse effects were categorized, and multivariate logistic regressions were performed to assess predictors of adverse effects.

Results: A total of 1615 older adults completed the survey, of whom 503 reported current use of cannabis and were included in this analysis. Adverse effects were reported by 308 participants (61.2%) and included dry mouth (36.2%), feeling high (25.9%), and adverse effects impacting balance (22.1%) and mental alertness (20.3%). Compared with participants aged 50-60 years, those aged 70 years and older had lower odds of reporting any adverse effects (odds ratio (OR) 0.524, 95% confidence interval (CI) 0.303-0.906) or adverse effects impacting mental alertness (OR 0.318, 95% CI 0.172-0.588). Female participants had higher odds of reporting any adverse effect (OR 1.989, 95% CI 1.332-2971) or adverse effects impacting balance (OR 1.930, 95% CI 1.198-3.109).

Conclusions: Adverse effects to cannabis are common amongst community-dwelling older adults. Increased education and guidance regarding adverse effects of cannabis, including the composition and dose of cannabis products, may help increase safe use by this population.

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加拿大老年人自我报告的大麻不良反应患病率：一项横断面分析。

背景和目的：尽管加拿大老年人越来越多地使用大麻，但对这一人群的大麻安全性知之甚少，特别是在非临床环境中。本研究的目的是描述社区居住的加拿大老年人使用大麻所经历的自我报告的不良反应。方法：50岁及以上的加拿大人完成了一项关于他们对大麻的知识、看法和经历的在线调查。要求报告目前使用大麻的答复者报告过去一年中与其使用大麻有关的任何不利影响。对不良反应进行分类，并进行多变量logistic回归来评估不良反应的预测因子。结果：共有1615名老年人完成了调查，其中503人报告目前使用大麻，并被纳入本分析。308名参与者（61.2%）报告了不良反应，包括口干（36.2%）、感觉兴奋（25.9%）、影响平衡（22.1%）和精神警觉（20.3%）的不良反应。与50-60岁的参与者相比，70岁及以上的参与者报告任何不良反应的几率较低（优势比（OR） 0.524, 95%可信区间（CI） 0.303-0.906）或影响精神警觉性的不良反应（OR 0.318, 95% CI 0.172-0.588）。女性参与者报告任何不良反应（OR 1.989, 95% CI 1.332-2971）或影响平衡的不良反应（OR 1.930, 95% CI 1.198-3.109）的几率更高。结论：大麻的不良反应在社区居住的老年人中很常见。加强关于大麻不利影响的教育和指导，包括大麻产品的成分和剂量，可能有助于增加这一人群的安全使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drugs & Aging 医学-老年医学

CiteScore

5.50

自引率

7.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Drugs & Aging delivers essential information on the most important aspects of drug therapy to professionals involved in the care of the elderly. The journal addresses in a timely way the major issues relating to drug therapy in older adults including: the management of specific diseases, particularly those associated with aging, age-related physiological changes impacting drug therapy, drug utilization and prescribing in the elderly, polypharmacy and drug interactions.