[Current State of Intestinal Transplantation].

Abstract

According to the current practice guidelines of the German Medical Chamber, intestinal transplantation is the only causal option for complicated chronic intestinal failure. However, due to demanding immunological, perioperative, infectious challenges, intestinal transplantation is a complementary treatment option secondary to intestinal rehabilitation, after overt failure of parenteral supplementation. This review contains a selected summary of international literature and guidelines, as well as the transplant practice guidelines of the German Medical Chamber. The field of intestinal transplantation comprises a variety of single and combined transplant procedures which are tailored to individual patients and their comorbidities secondary to complicated chronic intestinal failure. The indication is typically preceded by intense intestinal rehabilitation. Nowadays, around 100-150 intestinal transplants are performed worldwide, resulting in 1- and 3- year survival rates of almost 80 and 70%, respectively. This makes intestinal transplantation the rarest of all vascularised organ transplants which is typically only indicated after all modern measures of intestinal rehabilitation have been exploited.