Amir Asghari Baghkheirati, Reza Golmohammadi, Mohammad Hadi Sekhavati, Jamshid Razmyar, Mohammad Ali Abyazi
{"title":"Recombinant Antimicrobial Peptides (rAMPs); Potential Applications in Medicine and Veterinary Medicine: A Review.","authors":"Amir Asghari Baghkheirati, Reza Golmohammadi, Mohammad Hadi Sekhavati, Jamshid Razmyar, Mohammad Ali Abyazi","doi":"10.30498/ijb.2024.455700.3913","DOIUrl":null,"url":null,"abstract":"<p><p>Antibiotic resistance has become a major public health concern worldwide. Treatment of humans and animals is becoming increasingly challenging due to antibiotic resistance. Antibiotic-resistant bacteria can be transmitted from animals to humans by several routes, including direct contact, contaminated food or water, or environmental exposure. Various factors contribute to the rising problem, such as the widespread and indiscriminate exploitation of antimicrobials in both human and animal healthcare, over-prescription, misuse of antibiotics, the role of agriculture in spreading antibiotic resistance, and poor animal husbandry practices. According to the preliminary findings, recombinant antimicrobial peptides are an interesting novel area of biotechnology and medical innovation that might be employed as a secure and effective substitute for antibiotics. In this review study, we briefly examine the factors contributing to the rise of antibiotic resistance. We then introduce and discuss recombinant antimicrobial peptides as a promising strategy to address this growing problem.</p>","PeriodicalId":14492,"journal":{"name":"Iranian Journal of Biotechnology","volume":"22 4","pages":"e3913"},"PeriodicalIF":1.6000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11993234/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Biotechnology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.30498/ijb.2024.455700.3913","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Antibiotic resistance has become a major public health concern worldwide. Treatment of humans and animals is becoming increasingly challenging due to antibiotic resistance. Antibiotic-resistant bacteria can be transmitted from animals to humans by several routes, including direct contact, contaminated food or water, or environmental exposure. Various factors contribute to the rising problem, such as the widespread and indiscriminate exploitation of antimicrobials in both human and animal healthcare, over-prescription, misuse of antibiotics, the role of agriculture in spreading antibiotic resistance, and poor animal husbandry practices. According to the preliminary findings, recombinant antimicrobial peptides are an interesting novel area of biotechnology and medical innovation that might be employed as a secure and effective substitute for antibiotics. In this review study, we briefly examine the factors contributing to the rise of antibiotic resistance. We then introduce and discuss recombinant antimicrobial peptides as a promising strategy to address this growing problem.
期刊介绍:
Iranian Journal of Biotechnology (IJB) is published quarterly by the National Institute of Genetic Engineering and Biotechnology. IJB publishes original scientific research papers in the broad area of Biotechnology such as, Agriculture, Animal and Marine Sciences, Basic Sciences, Bioinformatics, Biosafety and Bioethics, Environment, Industry and Mining and Medical Sciences.