Prevalence of Human Immunodeficiency Virus, Hepatitis B, Hepatitis C and Syphilis among Antenatal Patients, Gastroenterology Patients and Blood Donors in Public Hospitals in Lagos.

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Nigerian Postgraduate Medical Journal Pub Date : 2025-04-01 Epub Date: 2025-05-14 DOI:10.4103/npmj.npmj_28_25
Kehinde Sharafadeen Okunade, Emuobor Odeghe, Damilola O Akinlawon, Rita O Oladele
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引用次数: 0

Abstract

Background: Blood-borne infections remain a significant public health challenge globally. Understanding their prevalence and risk factors is crucial for implementing preventive measures.

Objective: The objective of the study was to determine the prevalence of blood-borne infections, including human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis, among patients attending public hospitals in Lagos, Nigeria.

Subjects and methods: This was a cross-sectional study involving 352 participants, recruited from the antenatal, gastroenterology clinics and prospective donors from the blood banks in four general and one tertiary hospital in Lagos, Nigeria. Data were collected on demographic characteristics, risk factors and disease prevalence using structured questionnaires, and laboratory testing was performed using the B21147-01 HIV-HCV-HBsAg-Syphilis Combo Rapid Test.

Results: The mean age of participants was 37.2 ± 11.0 years. The majority were female (66.8%) and married (80.7%). The prevalence of HIV, hepatitis B surface antigen (HBsAg) anti-HCV, and syphilis was 24.4%, 23.3%, 2.6% and 0.3%, respectively. There was significantly increased odds of HIV infection among participants with a history of sexually transmitted infections (adjusted odds ratio [AOR] = 2.3, 95% confidence interval [CI] = 1.0-5.1), and those who had skilled occupations (AOR = 4.5, 95% CI = 1.5-13.3). Participants with a family history of either HBV, HCV, chronic liver disease or hepatocellular carcinoma had significantly increased odds of being HBsAg positive (AOR = 7.8, 95% CI = 2.1-29.42).

Conclusion: Blood-borne viral infections are highly prevalent among people attending hospitals in Lagos, Nigeria. Enhanced screening, awareness and risk reduction education are recommended to reduce the burden of these infections.

拉各斯公立医院产前患者、胃肠病患者和献血者中人类免疫缺陷病毒、乙型肝炎、丙型肝炎和梅毒的流行情况。
背景:血源性感染仍然是全球重大的公共卫生挑战。了解其流行情况和危险因素对于实施预防措施至关重要。目的:本研究的目的是确定血液传播感染的流行情况,包括人类免疫缺陷病毒(HIV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和梅毒,在尼日利亚拉各斯公立医院就诊的患者中。对象和方法:这是一项涉及352名参与者的横断面研究,他们来自尼日利亚拉各斯四家普通医院和一家三级医院的产前、胃肠病学诊所和血库的潜在献血者。采用结构化问卷收集人口统计学特征、危险因素和疾病患病率数据,并使用B21147-01 hiv - hcv - hbsag -梅毒联合快速检测试剂盒进行实验室检测。结果:参与者平均年龄为37.2±11.0岁。以女性(66.8%)和已婚(80.7%)居多。HIV患病率为24.4%,乙型肝炎表面抗原(HBsAg)抗- hcv患病率为23.3%,梅毒患病率为2.6%,梅毒患病率为0.3%。有性传播感染史的参与者(调整优势比[AOR] = 2.3, 95%可信区间[CI] = 1.0-5.1)和有熟练职业的参与者(调整优势比[AOR] = 4.5, 95%可信区间[CI] = 1.5-13.3)感染艾滋病毒的几率显著增加。有HBV、HCV、慢性肝病或肝细胞癌家族史的参与者HBsAg阳性的几率显著增加(AOR = 7.8, 95% CI = 2.1-29.42)。结论:血源性病毒感染在尼日利亚拉各斯医院就诊的人群中非常普遍。建议加强筛查、提高认识和减少风险教育,以减轻这些感染的负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Nigerian Postgraduate Medical Journal
Nigerian Postgraduate Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.90
自引率
0.00%
发文量
52
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