Surgical outcomes in mediastinal mature teratoma.

IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Indian Journal of Thoracic and Cardiovascular Surgery Pub Date : 2025-05-01 Epub Date: 2025-01-18 DOI:10.1007/s12055-024-01882-8

Mohan Venkatesh Pulle, Anmol Bhan, Sukhram Bishnoi, Belal Bin Asaf, Harsh Vardhan Puri, Sumit Bangeria, Manan Bharatkumar Parikh, Arvind Kumar

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引用次数: 0

Abstract

Background: This study was aimed at reporting the clinical characteristics and perioperative surgical outcomes of mediastinal mature teratoma managed in a single surgical unit.

Methods: This is a retrospective analysis of 35 cases of mediastinal mature teratoma cases managed in a tertiary level thoracic surgery center over 10 years. A comprehensive analysis of perioperative surgical outcomes including complications was performed.

Results: Males (n = 22, 62.8%) were predominant in the study group. Mean age of the cohort was 31.2 ± 13.3 years. The diagnosis was unruptured mature teratoma in 17(48.6%), ruptured mature teratoma in 8 (22.8%) and mature cystic teratoma in 10 (28.6%) patients. The mean duration from symptoms was 5.5 months (range: 1 - 84 months). Open surgery was done in 22 patients (62.8%) followed by video-assisted thoracoscopic surgery in 4 (11.4%) and robotic surgery in 9 patients (25.7%). Conversion from minimal access surgery to open surgery was in 2 patients (5.7%). The mean duration of intercostal chest drainage (ICD) was 6.3 ± 1.3 days, and mean hospital stay averaged 5.8 ± 2.7 days. Most common postoperative complication was prolonged post-operative air leak (> 7 days) in 5 patients (14.3%). The peri-operative mortality was in 1 (2.8%) patient. Ruptured teratoma was a strong predictor of postoperative complications (p = 0.008).

Conclusion: Complete surgical resection is primary and effective treatment modality for mediastinal mature teratoma. A tailored approach is needed, considering the factors like tumor size, location, and relation with surrounding structures.

Graphical abstract:

Supplementary information: The online version contains supplementary material available at 10.1007/s12055-024-01882-8.

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纵隔成熟畸胎瘤的手术效果。

背景：本研究旨在报道纵隔成熟畸胎瘤的临床特点和围手术期手术结果。方法：对某三级胸外科中心10年来收治的35例纵隔成熟畸胎瘤进行回顾性分析。对围手术期手术结果及并发症进行综合分析。结果：研究组以男性为主（n = 22，占62.8%）。队列的平均年龄为31.2±13.3岁。未破裂的成熟畸胎瘤17例（48.6%），破裂的成熟畸胎瘤8例（22.8%），成熟囊性畸胎瘤10例（28.6%）。平均症状消失时间为5.5个月（范围：1 - 84个月）。开放手术22例（62.8%），电视胸腔镜手术4例（11.4%），机器人手术9例（25.7%）。2例患者（5.7%）从最小通道手术转为开放手术。肋间胸腔引流（ICD）平均持续时间为6.3±1.3天，平均住院时间为5.8±2.7天。5例（14.3%）患者术后最常见的并发症为术后漏气时间延长（7天）。围手术期死亡1例（2.8%）。畸胎瘤破裂是术后并发症的重要预测因素（p = 0.008）。结论：手术完全切除是治疗纵隔成熟畸胎瘤的主要有效方法。考虑到肿瘤大小、位置以及与周围结构的关系等因素，需要量身定制的方法。图片摘要：补充资料：在线版本包含补充资料，网址为10.1007/s12055-024-01882-8。

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来源期刊

Indian Journal of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.20

自引率

14.30%

发文量

141

期刊介绍： The primary aim of the Indian Journal of Thoracic and Cardiovascular Surgery is education. The journal aims to dissipate current clinical practices and developments in the area of cardiovascular and thoracic surgery. This includes information on cardiovascular epidemiology, aetiopathogenesis, clinical manifestation etc. The journal accepts manuscripts from cardiovascular anaesthesia, cardiothoracic and vascular nursing and technology development and new/innovative products.The journal is the official publication of the Indian Association of Cardiovascular and Thoracic Surgeons which has a membership of over 1000 at present.DescriptionThe journal is the official organ of the Indian Association of Cardiovascular-Thoracic Surgeons. It was started in 1982 by Dr. Solomon Victor and ws being published twice a year up to 1996. From 2000 the editorial office moved to Delhi. From 2001 the journal was extended to quarterly and subsequently four issues annually have been printed out at time and regularly without fail. The journal receives manuscripts from members and non-members and cardiovascular surgeons. The manuscripts are peer reviewed by at least two or sometimes three or four reviewers who are on the panel. The manuscript process is now completely online. Funding the journal comes partially from the organization and from revenue generated by subscription and advertisement.