{"title":"Massive Duodenal Angiolipoma: A Rare Case with Severe Haemorrhage.","authors":"Hoang Duc Dong, Thai Van Nguyen, Thanh Binh Mai","doi":"10.12890/2025_005303","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Duodenal angiolipoma is an exceptionally rare and often misdiagnosed clinical entity, characterized by a benign proliferation of adipose and vascular tissues. When large, these lesions pose a significant diagnostic challenge, frequently mimicking malignancy during endoscopic evaluation, especially in cases of severe gastrointestinal haemorrhage. Rapid recognition and decisive management are critical, requiring hemodynamic stabilization, advanced diagnostic tools, and expert intervention to prevent life-threatening complications.</p><p><strong>Case description: </strong>We present the case of a 71-year-old female who arrived at the emergency department with acute upper gastrointestinal haemorrhage and hemodynamic instability. Immediate resuscitation, including haemostatic pharmacotherapy and blood transfusion, was initiated. Subsequent endoscopic evaluation, enhanced by endoscopic ultrasound, revealed a 2 × 3 cm duodenal lesion with a high-risk vascular structure. To prevent further haemorrhage, the tumour was swiftly ligated with an endoloop and excised via polypectomy. Histopathological analysis confirmed duodenal angiolipoma, characterized by mature adipose tissue interwoven with proliferative vascular elements. Following intervention, the patient recovered rapidly, with no recurrence of haemorrhage, and was discharged in stable condition.</p><p><strong>Conclusion: </strong>Massive duodenal angiolipomas causing severe haemorrhage to require appropriate medical haemostasis and resuscitation. Timely recognition and diagnosis via endoscopic ultrasound are vital. Endoscopic resection is a safe and effective treatment that prevents recurring bleeding in this case.</p><p><strong>Learning points: </strong>Duodenal angiolipomas are rare benign tumours that can mimic malignancies and cause life-threatening gastrointestinal bleeding.Endoscopic ultrasound and computed tomography scan are essential for differentiating these tumours from malignant lesions and guiding treatment.Endoscopic resection is a safe, minimally invasive option for duodenal angiolipoma to prevent recurrent bleeding, especially in resource-limited settings.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 5","pages":"005303"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061200/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of case reports in internal medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12890/2025_005303","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Duodenal angiolipoma is an exceptionally rare and often misdiagnosed clinical entity, characterized by a benign proliferation of adipose and vascular tissues. When large, these lesions pose a significant diagnostic challenge, frequently mimicking malignancy during endoscopic evaluation, especially in cases of severe gastrointestinal haemorrhage. Rapid recognition and decisive management are critical, requiring hemodynamic stabilization, advanced diagnostic tools, and expert intervention to prevent life-threatening complications.
Case description: We present the case of a 71-year-old female who arrived at the emergency department with acute upper gastrointestinal haemorrhage and hemodynamic instability. Immediate resuscitation, including haemostatic pharmacotherapy and blood transfusion, was initiated. Subsequent endoscopic evaluation, enhanced by endoscopic ultrasound, revealed a 2 × 3 cm duodenal lesion with a high-risk vascular structure. To prevent further haemorrhage, the tumour was swiftly ligated with an endoloop and excised via polypectomy. Histopathological analysis confirmed duodenal angiolipoma, characterized by mature adipose tissue interwoven with proliferative vascular elements. Following intervention, the patient recovered rapidly, with no recurrence of haemorrhage, and was discharged in stable condition.
Conclusion: Massive duodenal angiolipomas causing severe haemorrhage to require appropriate medical haemostasis and resuscitation. Timely recognition and diagnosis via endoscopic ultrasound are vital. Endoscopic resection is a safe and effective treatment that prevents recurring bleeding in this case.
Learning points: Duodenal angiolipomas are rare benign tumours that can mimic malignancies and cause life-threatening gastrointestinal bleeding.Endoscopic ultrasound and computed tomography scan are essential for differentiating these tumours from malignant lesions and guiding treatment.Endoscopic resection is a safe, minimally invasive option for duodenal angiolipoma to prevent recurrent bleeding, especially in resource-limited settings.
期刊介绍:
The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.