Academic Detailing to Enhance Adoption of Clinical Decision Support for Patients at Risk of Opioid Overdose.

IF 2.1 2区 医学 Q4 MEDICAL INFORMATICS
Applied Clinical Informatics Pub Date : 2025-03-01 Epub Date: 2025-05-07 DOI:10.1055/a-2508-7086
Sarah Hussain, Harold Lehmann, Megan E Buresh, Timothy M Niessen, Michael I Fingerhood, Nazeer Ahmed, Kelly Cavallio, Andrew Maslen, Amy M Knight
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Abstract

Background:  Not all patients at risk for opioid overdose are prescribed naloxone when discharged from the emergency department or hospital. Clinical decision support (CDS) can be used to promote clinical best practices, such as naloxone prescribing; however, it may be ignored due to knowledge deficiencies or alert fatigue.

Objectives:  Assess the effect of academic detailing on responses to a CDS alert recommending a naloxone prescription for patients at risk of opioid overdose.

Methods:  A pre/postquality improvement study of 2,161 active providers at a 400-bed academic medical center. The first intervention was an educational email to all providers. The second intervention was individual emails to 150 providers who infrequently ordered naloxone in response to the alert. The main outcome measure was prescription-to-alert ratios, defined as the number of naloxone prescriptions signed in response to the alert divided by the number of times the alert fired.

Results:  The first academic detailing intervention resulted in a prescription-to-alert ratio increase from 32.6 to 51.7%, a 19.1% absolute increase when comparing the approximately 8 months before and after the email was sent (95% confidence interval [CI]: 16.3-21.9%, p < 0.001). The second intervention resulted in an increased prescription-to-alert ratio from 9.3 to 50.6%, an absolute increase of 41.3% when comparing the nearly 8 months before and after the emails were sent (95% CI: 36.9-45.7%, p < 0.001). Improvements were seen across all services and all provider roles, particularly for advanced practice providers, and were sustained for 8 months.

Conclusion:  Academic detailing can be used to augment responses to CDS for patients with opioid dependence. Further study is needed to see if this effect can be replicated with CDS for other high priority conditions, and whether academic detailing with one alert might improve responses to other alerts as well, potentially decreasing alert fatigue.

加强对阿片类药物过量风险患者的临床决策支持的学术细节。
背景:并非所有有阿片类药物过量风险的患者在从急诊科或医院出院时都使用纳洛酮。临床决策支持(CDS)可用于促进临床最佳做法,如纳洛酮处方;但也可能因知识不足或警觉性疲劳而被忽略。目的:评估学术细节对CDS警报反应的影响,建议对阿片类药物过量风险的患者使用纳洛酮处方。方法:对一家拥有400张床位的学术医疗中心的2161名在职医务人员进行了前后质量改进研究。第一个干预措施是向所有提供者发送教育电子邮件。第二项干预措施是给150家供应商发送个人电子邮件,这些供应商在收到警报后很少订购纳洛酮。主要结局指标是处方-警报比率,定义为响应警报而签署的纳洛酮处方数除以警报发出的次数。结果:第一次学术详细干预导致处方-警告率从32.6增加到51.7%,与发送电子邮件前后大约8个月相比,绝对增加了19.1%(95%置信区间[CI]: 16.3-21.9%, p)结论:学术详细干预可用于增加阿片类药物依赖患者对CDS的反应。需要进一步的研究,看看这种效果是否可以在CDS中复制到其他高优先级条件,以及一个警报的学术细节是否也可以改善对其他警报的反应,潜在地减少警报疲劳。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Applied Clinical Informatics
Applied Clinical Informatics MEDICAL INFORMATICS-
CiteScore
4.60
自引率
24.10%
发文量
132
期刊介绍: ACI is the third Schattauer journal dealing with biomedical and health informatics. It perfectly complements our other journals Öffnet internen Link im aktuellen FensterMethods of Information in Medicine and the Öffnet internen Link im aktuellen FensterYearbook of Medical Informatics. The Yearbook of Medical Informatics being the “Milestone” or state-of-the-art journal and Methods of Information in Medicine being the “Science and Research” journal of IMIA, ACI intends to be the “Practical” journal of IMIA.
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