Healthcare-associated infection and unfavourable outcomes during a one-year follow-up after discharge: a single-center study.

IF 1.4 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International journal of occupational medicine and environmental health Pub Date : 2025-04-23 Epub Date: 2025-04-16 DOI:10.13075/ijomeh.1896.02473

Beata Czerniak, Wioletta Banaś, Jacek Budzyński

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引用次数: 0

Abstract

Objectives: Healthcare-associated infections (HAIs) are persistent problem in contemporary in-hospital patients' treatment but they are recognized as potentially preventable. The influence of HAI on patients' outcomes after discharge is not fully acknowledged. The authors conducted the study to determine the associations between HAI and length of hospitalization, all-cause in-hospital death, need for treatment in the intensive care unit (ICU), and rehospitalization within 14 days, 30 days, and 365 days.

Material and methods: On the basis of inclusion criteria, 631 of 5322 (11.86%) inpatients were enrolled to the study, for whom the authors determined, among other factors, medical history, Activities of Daily Living (ADL) score and Nutritional Risk Screening 2002 (NRS-2002) score, nutritional status (using anthropometric characteristics and bioelectrical impedance analysis), and Charlson Comorbidity Index score.

Results: Healthcare-associated infections occurred in 17.9% of the inpatients enrolled to the study. Healthcare-associated infections were linked with greater length of in-hospital stay (LOS), risk of in-hospital death, transfer to the ICU, and hospital readmission within 14 days and 30 days. In multivariate analysis, HAI was the strongest risk factor for LOS prolongation, need for treatment in the ICU (OR = 15.26, 95% CI: 3.0-77.8, p < 0.01), and all-cause in-hospital death (OR = 10.73, 95% CI: 3.9-29.69, p < 0.001), alongside NRS-2002 and ADL scores. Healthcare-associated infections did not affect the risk of 14- and 30-day and 1-year readmissions in multivariate analysis, which were related to, among other factors, ADL score and mode of admission.

Conclusions: Healthcare-associated infections statistically and significantly affected only outcomes related to the current hospitalization, across both univariate and multivariate analyses. Int J Occup Med Environ Health. 2025;38(2):179-89.

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出院后一年随访期间医疗保健相关感染和不良结果：一项单中心研究

目的：医疗保健相关感染（HAIs）是当代住院患者治疗中持续存在的问题，但它们被认为是潜在的可预防的。HAI对患者出院后预后的影响尚未得到充分认识。作者进行了这项研究，以确定HAI与住院时间、院内全因死亡、重症监护病房（ICU）治疗需求以及14天、30天和365天内再次住院之间的关系。材料和方法：根据纳入标准，5322例住院患者中有631例（11.86%）纳入研究，作者确定了病史、日常生活活动（ADL）评分和营养风险筛查2002 （NRS-2002）评分、营养状况（采用人体特征和生物电阻抗分析）和Charlson合并症指数评分等因素。结果：参与研究的住院患者中有17.9%发生了医疗相关感染。医疗保健相关感染与更长的住院时间（LOS）、院内死亡风险、转至ICU以及在14天和30天内再次住院有关。在多因素分析中，与NRS-2002和ADL评分相比，HAI是LOS延长、ICU治疗需求（OR = 15.26, 95% CI: 3.0-77.8, p < 0.01）和院内全因死亡（OR = 10.73, 95% CI: 3.9-29.69, p < 0.001）的最强危险因素。在多变量分析中，医疗保健相关感染不影响14天、30天和1年再入院的风险，这与ADL评分和入院方式等因素有关。结论：在单变量和多变量分析中，与医疗保健相关的感染仅对当前住院治疗相关的结果有统计学上的显著影响。中华医学与环境卫生杂志，2015;38(2):179-89。

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来源期刊

International journal of occupational medicine and environmental health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.40

自引率

5.00%

发文量

审稿时长

7.5 months

期刊介绍： The Journal is dedicated to present the contemporary research in occupational and environmental health from all over the world. It publishes works concerning: occupational and environmental: medicine, epidemiology, hygiene and toxicology; work physiology and ergonomics, musculoskeletal problems; psychosocial factors at work, work-related mental problems, aging, work ability and return to work; working hours, shift work; reproductive factors and endocrine disruptors; radiation, ionizing and non-ionizing health effects; agricultural hazards; work safety and injury and occupational health service; climate change and its effects on health; omics, genetics and epigenetics in occupational and environmental health; health effects of exposure to nanoparticles and nanotechnology products; human biomarkers in occupational and environmental health, intervention studies, clinical sciences’ achievements with potential to improve occupational and environmental health.