A Case of Infective Endocarditis Caused by Beta-Lactam Resistant Streptococcus Alactolyticus.

Q3 Medicine
European journal of case reports in internal medicine Pub Date : 2025-04-10 eCollection Date: 2025-01-01 DOI:10.12890/2025_005367
Melina Ntoga, Vasileios Emmanouil, Eirini Terzi, Vasilios Petrakis, Periklis Panagopoulos, Dimitrios Papazoglou
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引用次数: 0

Abstract

Background: Streptococcus alactolyticus is a rare cause of human infections, with limited reports of infective endocarditis (IE).

Case report: We present a case of a 68-year-old male with severe aortic stenosis who developed S. alactolyticus associated IE resistant to beta-lactams. Initial treatment with vancomycin and gentamicin led to temporary improvement, but the patient later developed complications, including splenic infarction and an aortic root abscess. Despite intensified antimicrobial therapy, he ultimately succumbed to multiorgan failure.

Conclusion: This case underscores the importance of early identification of resistant pathogens, appropriate antibiotic selection, and vigilant monitoring for complications. The rising incidence of beta-lactam resistance in streptococcal infections highlights the need for ongoing epidemiological surveillance and research to optimize treatment strategies.

Learning points: Streptococcus alactolyticus is a rare but emerging cause of infective endocarditis that necessitates increased clinical awareness.

耐β -内酰胺溶乳酸链球菌致感染性心内膜炎1例。
背景:溶乳酸链球菌是一种罕见的人类感染原因,关于感染性心内膜炎(IE)的报道有限。病例报告:我们报告一例68岁男性严重主动脉瓣狭窄,并发乳酸链球菌相关IE,对-内酰胺耐药。最初使用万古霉素和庆大霉素治疗导致暂时改善,但患者后来出现并发症,包括脾梗死和主动脉根脓肿。尽管加强了抗菌治疗,他最终还是死于多器官衰竭。结论:该病例强调了早期发现耐药病原体、适当选择抗生素和警惕监测并发症的重要性。链球菌感染中β -内酰胺耐药发生率的上升突出表明需要进行持续的流行病学监测和研究,以优化治疗策略。学习要点:溶乳酸链球菌是一种罕见但新出现的感染性心内膜炎的原因,需要提高临床意识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.10
自引率
0.00%
发文量
166
审稿时长
8 weeks
期刊介绍: The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.
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