{"title":"A Case of Infective Endocarditis Caused by Beta-Lactam Resistant <i>Streptococcus Alactolyticus</i>.","authors":"Melina Ntoga, Vasileios Emmanouil, Eirini Terzi, Vasilios Petrakis, Periklis Panagopoulos, Dimitrios Papazoglou","doi":"10.12890/2025_005367","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong><i>Streptococcus alactolyticus</i> is a rare cause of human infections, with limited reports of infective endocarditis (IE).</p><p><strong>Case report: </strong>We present a case of a 68-year-old male with severe aortic stenosis who developed <i>S. alactolyticus</i> associated IE resistant to beta-lactams. Initial treatment with vancomycin and gentamicin led to temporary improvement, but the patient later developed complications, including splenic infarction and an aortic root abscess. Despite intensified antimicrobial therapy, he ultimately succumbed to multiorgan failure.</p><p><strong>Conclusion: </strong>This case underscores the importance of early identification of resistant pathogens, appropriate antibiotic selection, and vigilant monitoring for complications. The rising incidence of beta-lactam resistance in streptococcal infections highlights the need for ongoing epidemiological surveillance and research to optimize treatment strategies.</p><p><strong>Learning points: </strong><i>Streptococcus alactolyticus</i> is a rare but emerging cause of infective endocarditis that necessitates increased clinical awareness.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 5","pages":"005367"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061226/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of case reports in internal medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12890/2025_005367","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Streptococcus alactolyticus is a rare cause of human infections, with limited reports of infective endocarditis (IE).
Case report: We present a case of a 68-year-old male with severe aortic stenosis who developed S. alactolyticus associated IE resistant to beta-lactams. Initial treatment with vancomycin and gentamicin led to temporary improvement, but the patient later developed complications, including splenic infarction and an aortic root abscess. Despite intensified antimicrobial therapy, he ultimately succumbed to multiorgan failure.
Conclusion: This case underscores the importance of early identification of resistant pathogens, appropriate antibiotic selection, and vigilant monitoring for complications. The rising incidence of beta-lactam resistance in streptococcal infections highlights the need for ongoing epidemiological surveillance and research to optimize treatment strategies.
Learning points: Streptococcus alactolyticus is a rare but emerging cause of infective endocarditis that necessitates increased clinical awareness.
期刊介绍:
The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.