Palliative sedation with propofol for refractory agitation.

IF 2 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES

BMJ Supportive & Palliative Care Pub Date : 2025-05-02 DOI:10.1136/spcare-2025-005524

Kelvin Lou, Brian Li, Shikha Minhas, Shalini Nayar

引用次数: 0

Abstract

Palliative sedation is a useful intervention to manage refractory symptoms at the end of life. Currently, there is limited research on approaches to managing symptoms refractory to standard sedation protocols. Expanding awareness of therapeutic options is essential for improving management of refractory cases. Propofol, a short-acting anaesthetic, may be a valuable option when conventional sedatives at high doses fail to achieve adequate symptom relief. We present the case of a 40-year-old woman with high-grade metastatic ovarian cancer with refractory agitation that was successfully managed with propofol for palliative sedation.

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异丙酚缓和镇静治疗难治性躁动。

姑息性镇静是一种有效的干预措施，以管理难治性症状在生命结束。目前，对标准镇静方案难以治疗的症状的治疗方法研究有限。扩大对治疗选择的认识对于改善难治性病例的管理至关重要。异丙酚是一种短效麻醉剂，当传统的大剂量镇静剂不能充分缓解症状时，异丙酚可能是一种有价值的选择。我们提出的情况下，一个40岁的妇女高级别转移性卵巢癌难治性躁动，成功地管理与异丙酚姑息性镇静。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMJ Supportive & Palliative Care Medicine-Medicine (miscellaneous)

CiteScore

4.60

自引率

7.40%

发文量

170

期刊介绍： Published quarterly in print and continuously online, BMJ Supportive & Palliative Care aims to connect many disciplines and specialties throughout the world by providing high quality, clinically relevant research, reviews, comment, information and news of international importance. We hold an inclusive view of supportive and palliative care research and we are able to call on expertise to critique the whole range of methodologies within the subject, including those working in transitional research, clinical trials, epidemiology, behavioural sciences, ethics and health service research. Articles with relevance to clinical practice and clinical service development will be considered for publication. In an international context, many different categories of clinician and healthcare workers do clinical work associated with palliative medicine, specialist or generalist palliative care, supportive care, psychosocial-oncology and end of life care. We wish to engage many specialties, not only those traditionally associated with supportive and palliative care. We hope to extend the readership to doctors, nurses, other healthcare workers and researchers in medical and surgical specialties, including but not limited to cardiology, gastroenterology, geriatrics, neurology, oncology, paediatrics, primary care, psychiatry, psychology, renal medicine, respiratory medicine.