The adjuvant therapy of edible herbal product including colchicum bulb, olive leaf, black cumin seeds, lavender flower, and ginger rhizome on the outcome of patients with severe and critical COVID-19: A double-blind randomized controlled clinical trial.

IF 1.9 Q3 CHEMISTRY, MEDICINAL

Avicenna Journal of Phytomedicine Pub Date : 2024-11-01 DOI:10.22038/AJP.2024.24633

Vahid Sebghatollahi, Mansour Siavash Dastjerdi, Farzin Ghiasi, Babak Alikiaii, Morteza Pourahmad, Afsaneh Yegdaneh, Mojtaba Akbari, Reza Ghadiri

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引用次数: 0

Abstract

Objective: The present study aimed at evaluating the effect of combination of medicinal plants, including Colchicum autumnal L., Olea europaea L., Nigella sativa L., Lavandula angustifolia L., and Zingiber officinale Roscoe, on the recovery and outcome of COVID-19 patients.

Materials and methods: This study was conducted on 150 COVID-19 patients. All patients received both pharmaceutical and supportive treatments. In addition to the standard care treatment, intervention group received two capsules of herbal medicine orally every 8 hours, while control group received placebo.

Results: Oxygen saturation percentage (SpO2) of the intervention group (median:88.00) was significantly higher than that of the control group (median:86.00), while C-reactive protein (CRP) of the intervention group (median:20.00) was significantly lower than that of the control group (median:28.00) at the time of hospital discharge (p<0.05).

Conclusion: The combination of studied medicinal plants could significantly reduce the oxygen requirement and oxygen therapy.

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秋水仙球茎、橄榄叶、黑孜然、薰衣草花、姜根等食疗产品对重症危重型COVID-19患者转归的辅助治疗：双盲随机对照临床试验

目的：本研究旨在评价秋水仙、油橄榄、黑草、薰衣草、生姜等药用植物联合治疗对COVID-19患者康复及转归的影响。材料与方法：本研究以150例新冠肺炎患者为研究对象。所有患者均接受药物治疗和支持性治疗。在标准护理治疗的基础上，干预组每8小时口服2粒中药胶囊，对照组给予安慰剂。结果：干预组患者出院时血氧饱和度（SpO2）（中位数：88.00）显著高于对照组（中位数：86.00），而c -反应蛋白（CRP）（中位数：20.00）显著低于对照组（中位数：28.00）。结论：所研究的药用植物联合使用可显著降低患者的需氧量和氧疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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