The clinical characteristics and response to head-up tilt test of patients with micturition syncope: single-center experience in China.

IF 3.9 3区医学 Q1 CLINICAL NEUROLOGY

Clinical Autonomic Research Pub Date : 2025-05-02 DOI:10.1007/s10286-025-01126-8

Jing Li, Xuan Xiao, Shunzhi He, Haitao Sun

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引用次数: 0

Abstract

Objective: This study compared clinical characteristics and response to head-up tilt test (HUTT) between micturition syncope (MS) and typical vasovagal syncope (VVS).

Methods: Consecutive patients who underwent nitroglycerin-potentiated HUTT were retrospectively dichotomized into two groups: those with a history of MS and those with a history of VVS. The patients with MS were further subdivided into patients with MS alone and with MS and at least one episode of VVS.

Results: A total of 2637 patients were enrolled: 204 had MS (MS alone in 103 and MS+VVS in 101), and 216 had typical VVS. Patients with MS were older (38.6 ± 13.1 vs. 36.3 ± 18.5, p = 0003) and more likely to be male (66.2% vs. 48.1%, p < 0.001). Multivariable analysis revealed that smoking habit (odds ratio [OR] 2.16, p < 0.0001), history of traumatic syncope (OR 2.24, p = 0.0001), and drinking alcohol before syncope (OR 2.63, p < 0.0001) were independently associated with MS. HUTT was positive in 141 (69.1%) patients with MS and in 144 (66.7%) patients with VVS (p = 0.592). Patients with MS showed more mixed (46.1% vs. 28.2%, p < 0.001) and vasodepressor forms (15.2% vs. 7.9%, p = 0.013) and fewer cardioinhibitory responses than others (7.4% vs. 30.6%, p < 0.001).

Conclusions: Compared with VVS, patients with MS have different clinical characteristics, and drinking alcohol was an important precipitating factor for MS. The positivity rate of HUTT is high and similar to that of VVS, although patients with MS show a higher prevalence of hypotensive responses.

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排尿性晕厥患者的临床特征及对平视倾斜试验的反应：中国单中心研究

目的：比较排尿性晕厥（MS）与典型血管迷走神经性晕厥（VVS）的临床特征及对仰卧倾斜试验（HUTT）的反应。方法：回顾性地将连续接受硝酸甘油强化HUTT的患者分为两组：有MS病史的患者和有VVS病史的患者。将多发性硬化症患者进一步细分为单纯多发性硬化症患者和多发性硬化症合并至少一次VVS发作患者。结果：共纳入2637例患者，其中204例为MS(103例为单纯MS， 101例为MS+VVS)， 216例为典型VVS。MS患者年龄较大（38.6±13.1 vs. 36.3±18.5,p = 0003），男性居多（66.2% vs. 48.1%, p）结论：MS患者与VVS患者具有不同的临床特征，饮酒是MS的重要诱发因素，虽然MS患者降压反应发生率较高，但HUTT阳性率与VVS相似。

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来源期刊

Clinical Autonomic Research 医学-临床神经学

CiteScore

7.40

自引率

6.90%

发文量

审稿时长

>12 weeks

期刊介绍： Clinical Autonomic Research aims to draw together and disseminate research work from various disciplines and specialties dealing with clinical problems resulting from autonomic dysfunction. Areas to be covered include: cardiovascular system, neurology, diabetes, endocrinology, urology, pain disorders, ophthalmology, gastroenterology, toxicology and clinical pharmacology, skin infectious diseases, renal disease. This journal is an essential source of new information for everyone working in areas involving the autonomic nervous system. A major feature of Clinical Autonomic Research is its speed of publication coupled with the highest refereeing standards.