Imaging of Geographic Atrophy: A Practical Approach.

IF 2.6 3区医学 Q2 OPHTHALMOLOGY

Ophthalmology and Therapy Pub Date : 2025-05-05 DOI:10.1007/s40123-025-01158-3

Gregor S Reiter, Enrico Borrelli, Rosa Dolz-Marco, Raymond Iezzi, Sophie J Bakri

引用次数: 0

Abstract

Geographic atrophy (GA) secondary to age-related macular degeneration is a chronic degenerative disease involving the retinal pigment epithelium, photoreceptors, and choriocapillaris leading to irreversible loss of visual function. Identification of imaging markers associated with GA development and progression has progressed over the past decades, moving from two-dimensional to three-dimensional imaging, as well as image interpretation using artificial intelligence. However, there is an open discussion about the "must-haves" for GA detection and follow-up as well as complementary imaging. This practical approach provides an overview of the advantages of key imaging modalities for GA and their applicability in clinical and experimental settings.

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地理萎缩成像：一种实用方法。

地理性萎缩（GA）继发于年龄相关性黄斑变性是一种慢性退行性疾病，涉及视网膜色素上皮、光感受器和绒毛膜毛细血管，导致视觉功能的不可逆丧失。在过去的几十年里，与GA的发展和进展相关的成像标记物的识别已经取得了进展，从二维成像到三维成像，以及使用人工智能进行图像解释。然而，关于GA检测和随访以及互补成像的“必备条件”存在公开讨论。这种实用的方法概述了GA的关键成像方式的优势及其在临床和实验环境中的适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmology and Therapy OPHTHALMOLOGY-

CiteScore

4.20

自引率

3.00%

发文量

157

审稿时长

6 weeks

期刊介绍： Aims and Scope Ophthalmology and Therapy is an international, open access, peer-reviewed (single-blind), and rapid publication journal. The scope of the journal is broad and will consider all scientifically sound research from preclinical, clinical (all phases), observational, real-world, and health outcomes research around the use of ophthalmological therapies, devices, and surgical techniques. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/series, trial protocols and short communications such as commentaries and editorials. Ophthalmology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. 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