Mit Chauhan, Masara Touza, John Paul Fox, Asma Jamil, Ruhma Ali, Alan Klukowicz, Nirav Mistry
{"title":"Clevidipine Induced Intrapulmonary Shunting in a Patient with Acute Type B Aortic Dissection.","authors":"Mit Chauhan, Masara Touza, John Paul Fox, Asma Jamil, Ruhma Ali, Alan Klukowicz, Nirav Mistry","doi":"10.12890/2025_005095","DOIUrl":null,"url":null,"abstract":"<p><p>Clevidipine is a short acting calcium channel blocker commonly used to treat uncontrolled hypertension. The common side-effects include depression, dizziness, and headache. Hypoxia from intrapulmonary shunting after clevidipine use has not been widely reported in the literature. We present a case of acute type B aortic dissection treated with esmolol and clevidipine complicated by hypoxia which resolved post discontinuation of clevidipine.</p><p><strong>Learning points: </strong>Clevidipine may be used as an adjunct to beta blockers if the patient is still hypertensive or beta blockers are contraindicated.Intrapulmonary shunting leading to hypoxia is a rare complication of clevidipine therapy and should be suspected in an otherwise hypoxic patient in whom all other diagnoses have been ruled out.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005095"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013237/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of case reports in internal medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12890/2025_005095","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Clevidipine is a short acting calcium channel blocker commonly used to treat uncontrolled hypertension. The common side-effects include depression, dizziness, and headache. Hypoxia from intrapulmonary shunting after clevidipine use has not been widely reported in the literature. We present a case of acute type B aortic dissection treated with esmolol and clevidipine complicated by hypoxia which resolved post discontinuation of clevidipine.
Learning points: Clevidipine may be used as an adjunct to beta blockers if the patient is still hypertensive or beta blockers are contraindicated.Intrapulmonary shunting leading to hypoxia is a rare complication of clevidipine therapy and should be suspected in an otherwise hypoxic patient in whom all other diagnoses have been ruled out.
期刊介绍:
The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.