Frailty-free life expectancy and its association with socio-economic characteristics: an analysis of the English Longitudinal Study of Ageing cohort study.

IF 7 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL
David R Sinclair, Asri Maharani, Andrew Kingston, Terence W O'Neill, Fiona E Matthews
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Abstract

Background: Frailty is more prevalent in socio-economically disadvantaged groups; however, little is known about how this translates to differences in the number of years people live with and without frailty. We investigate differences in frailty-free and frail life expectancies among population groups stratified by wealth, area deprivation, education and marital status.

Methods: The English Longitudinal Study of Ageing cohort study was used to follow the frailty trajectories of 15,003 individuals over 18 years. A multi-state model assessed the risk of transitioning between frailty states and death based on socio-economic characteristics. These risks were translated into state-specific life expectancies.

Results: Wealth had the strongest association with frailty-free and frail life expectancies. Increased wealth, reduced deprivation, higher educational attainment and marriage all correlate with increased frailty-free life expectancies and reduced frail life expectancies. At age 50, the wealthiest population quintile can expect to live 11.1 [10.1-12.1] years (women) and 9.8 [8.8-10.8] years (men) longer frailty-free than the poorest population quintile. The wealthiest quintile live less than half the number of years with frailty than the poorest quintile. There is no difference in frailty-free life expectancy between the poorest men and women; however, the wealthiest women have longer frailty-free life expectancies than the wealthiest men.

Conclusions: Large inequalities in frailty-free and frail life expectancies exist across socio-economic groups, with wealth and area deprivation the most important socio-economic determinants. Narrowing these inequalities may extend frailty-free life expectancies more for women than men, suggesting strategies to reduce disparities should consider both socio-economic factors and gender. Care policies should account for the geographical clustering of socio-economically disadvantaged populations. Reducing socio-economic inequalities could increase frailty-free life expectancies and reduce health and social care costs.

无衰弱预期寿命及其与社会经济特征的关系:英国老龄化纵向研究队列研究的分析。
背景:脆弱在社会经济弱势群体中更为普遍;然而,对于这如何转化为人们有虚弱和没有虚弱的寿命的差异,人们知之甚少。我们调查了按财富、地区剥夺、教育和婚姻状况分层的人群中无体弱和体弱预期寿命的差异。方法:采用英国老龄化纵向研究队列研究对15,003名18岁以上个体的衰弱轨迹进行跟踪研究。一个多状态模型根据社会经济特征评估了脆弱状态和死亡之间过渡的风险。这些风险被转化为各州的预期寿命。结果:财富与无虚弱和虚弱的预期寿命有最强烈的联系。财富的增加、贫困的减少、受教育程度的提高和婚姻水平的提高都与无体弱预期寿命的延长和体弱预期寿命的缩短有关。在50岁时,最富有的五分之一人口预计比最贫穷的五分之一人口多活11.1[10.1-12.1]年(女性)和9.8[8.8-10.8]年(男性)。最富有的五分之一人口比最贫穷的五分之一人口的衰弱年数少一半。最贫穷的男性和女性在无虚弱预期寿命方面没有差别;然而,最富有的女性比最富有的男性拥有更长的无虚弱寿命。结论:不同社会经济群体在无体弱和体弱预期寿命方面存在巨大的不平等,财富和地区剥夺是最重要的社会经济决定因素。缩小这些不平等可能会比男性更多地延长女性的无体弱预期寿命,这表明减少不平等的战略应同时考虑社会经济因素和性别因素。护理政策应考虑到社会经济上处于不利地位的人口的地理聚集。减少社会经济不平等可以提高无体弱的预期寿命,并降低保健和社会保健费用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Medicine
BMC Medicine 医学-医学:内科
CiteScore
13.10
自引率
1.10%
发文量
435
审稿时长
4-8 weeks
期刊介绍: BMC Medicine is an open access, transparent peer-reviewed general medical journal. It is the flagship journal of the BMC series and publishes outstanding and influential research in various areas including clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. In addition to research articles, the journal also publishes stimulating debates, reviews, unique forum articles, and concise tutorials. All articles published in BMC Medicine are included in various databases such as Biological Abstracts, BIOSIS, CAS, Citebase, Current contents, DOAJ, Embase, MEDLINE, PubMed, Science Citation Index Expanded, OAIster, SCImago, Scopus, SOCOLAR, and Zetoc.
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