{"title":"Trends in the applications of artificial intelligence in fatty liver diseases.","authors":"Tian-Ao Xie, Li-Li Liufu, Hui-Jin Chen, Hao-Lin Chen, Xin-Ting Hou, Xuan-Rui Wang, Meng-Yi Han, Yu-Kai Shan, Rui-Jing Shen, Zhong-Yu Wu, Shi-Jie Li, Sarun Juengpanich, Win Topatana","doi":"10.1007/s12072-025-10827-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Artificial intelligence (AI) has rapidly advanced and shows great potential in the prediction, diagnosis, treatment, and prognosis of fatty liver disease (FLD). This study aims to summarize AI's applications and emerging trends in FLD to inspire future research directions.</p><p><strong>Method: </strong>We analyzed 270 articles sourced from the Web of Science Core Collection published between 2006 and 2024. The study focuses on the medical application of AI in FLD, examining the contributions of authors, institutions, countries, keywords, and cited references.</p><p><strong>Results: </strong>AI is predominantly applied in FLD diagnosis, with progression from simple diagnostic tools to advanced methods for classifying FLD and assessing liver fat content. Moreover, the types of data used in AI development have evolved, incorporating a variety of new image and clinical data sources. AI is also being integrated into drug development and personalized nutritional therapies for FLD. Additionally, researchers are becoming increasingly interested in the application of AI to study FLD genes.</p><p><strong>Conclusion: </strong>We found that the applications of AI in FLD are mainly reflected in the prediction, diagnosis, therapy, and prognosis of FLD. In contrast to traditional medicine, AI has the potential to advance the fields of precision medicine and telemedicine, as well as to conserve additional social resources. Moreover, AI may help medical personnel from the perspective of traditional Chinese medicine, FLD prognosis, and the use of AI to analyze gene prediction and natural language processing (NLP).</p>","PeriodicalId":12901,"journal":{"name":"Hepatology International","volume":" ","pages":""},"PeriodicalIF":5.9000,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hepatology International","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12072-025-10827-1","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Artificial intelligence (AI) has rapidly advanced and shows great potential in the prediction, diagnosis, treatment, and prognosis of fatty liver disease (FLD). This study aims to summarize AI's applications and emerging trends in FLD to inspire future research directions.
Method: We analyzed 270 articles sourced from the Web of Science Core Collection published between 2006 and 2024. The study focuses on the medical application of AI in FLD, examining the contributions of authors, institutions, countries, keywords, and cited references.
Results: AI is predominantly applied in FLD diagnosis, with progression from simple diagnostic tools to advanced methods for classifying FLD and assessing liver fat content. Moreover, the types of data used in AI development have evolved, incorporating a variety of new image and clinical data sources. AI is also being integrated into drug development and personalized nutritional therapies for FLD. Additionally, researchers are becoming increasingly interested in the application of AI to study FLD genes.
Conclusion: We found that the applications of AI in FLD are mainly reflected in the prediction, diagnosis, therapy, and prognosis of FLD. In contrast to traditional medicine, AI has the potential to advance the fields of precision medicine and telemedicine, as well as to conserve additional social resources. Moreover, AI may help medical personnel from the perspective of traditional Chinese medicine, FLD prognosis, and the use of AI to analyze gene prediction and natural language processing (NLP).
人工智能(AI)在脂肪肝(FLD)的预测、诊断、治疗和预后方面发展迅速,显示出巨大的潜力。本研究旨在总结人工智能在FLD中的应用和新兴趋势,以启发未来的研究方向。方法:我们分析了2006年至2024年间发表的270篇来自Web of Science核心合集的文章。本研究侧重于人工智能在FLD中的医学应用,考察了作者、机构、国家、关键词和被引参考文献的贡献。结果:人工智能主要应用于FLD诊断,从简单的诊断工具发展到FLD分类和肝脏脂肪含量评估的先进方法。此外,人工智能开发中使用的数据类型也在不断发展,纳入了各种新的图像和临床数据源。人工智能还被整合到FLD的药物开发和个性化营养疗法中。此外,研究人员对应用人工智能研究FLD基因越来越感兴趣。结论:人工智能在FLD中的应用主要体现在FLD的预测、诊断、治疗和预后方面。与传统医学相比,人工智能有可能推动精准医疗和远程医疗领域的发展,并节省额外的社会资源。此外,AI可以从中医、FLD预后、利用AI分析基因预测和自然语言处理(NLP)等角度帮助医务人员。
期刊介绍:
Hepatology International is the official journal of the Asian Pacific Association for the Study of the Liver (APASL). This is a peer-reviewed journal featuring articles written by clinicians, clinical researchers and basic scientists is dedicated to research and patient care issues in hepatology. This journal will focus mainly on new and emerging technologies, cutting-edge science and advances in liver and biliary disorders.
Types of articles published:
-Original Research Articles related to clinical care and basic research
-Review Articles
-Consensus guidelines for diagnosis and treatment
-Clinical cases, images
-Selected Author Summaries
-Video Submissions