{"title":"Workforce Development in Genomic Data Science for Health: A Worldview.","authors":"Sindiswa T Lukhele, Verena Ras, Nicola Mulder","doi":"10.1146/annurev-genom-012224-122440","DOIUrl":null,"url":null,"abstract":"<p><p>Genomics has the potential to transform human health, biomedical research, and life sciences by providing deep insights into genetic variation and disease mechanisms. However, fully realizing these benefits requires a well-trained workforce equipped to handle, analyze, and interpret increasingly complex genomic and linked datasets. The rapid evolution of sequencing technologies, machine learning, and data science tools has heightened the demand for professionals proficient in bioinformatics, high-performance computing, and genomic data governance. This review presents a global perspective on workforce development in genomic data science, detailing key competencies necessary for both research and clinical applications. We discuss some of the existing training programs, competency frameworks, and regional approaches to skills development while identifying gaps in education, infrastructure, and accessibility. Additionally, we explore the integration of genomic data science into healthcare, addressing challenges such as equitable access to training and the need for cross-disciplinary expertise. Tackling these challenges is essential for cultivating a diverse, skilled workforce capable of driving advancements in genomic research, precision medicine, and public health.</p>","PeriodicalId":8231,"journal":{"name":"Annual review of genomics and human genetics","volume":" ","pages":""},"PeriodicalIF":7.7000,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual review of genomics and human genetics","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1146/annurev-genom-012224-122440","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
引用次数: 0
Abstract
Genomics has the potential to transform human health, biomedical research, and life sciences by providing deep insights into genetic variation and disease mechanisms. However, fully realizing these benefits requires a well-trained workforce equipped to handle, analyze, and interpret increasingly complex genomic and linked datasets. The rapid evolution of sequencing technologies, machine learning, and data science tools has heightened the demand for professionals proficient in bioinformatics, high-performance computing, and genomic data governance. This review presents a global perspective on workforce development in genomic data science, detailing key competencies necessary for both research and clinical applications. We discuss some of the existing training programs, competency frameworks, and regional approaches to skills development while identifying gaps in education, infrastructure, and accessibility. Additionally, we explore the integration of genomic data science into healthcare, addressing challenges such as equitable access to training and the need for cross-disciplinary expertise. Tackling these challenges is essential for cultivating a diverse, skilled workforce capable of driving advancements in genomic research, precision medicine, and public health.
期刊介绍:
Since its inception in 2000, the Annual Review of Genomics and Human Genetics has been dedicated to showcasing significant developments in genomics as they pertain to human genetics and the human genome. The journal emphasizes genomic technology, genome structure and function, genetic modification, human variation and population genetics, human evolution, and various aspects of human genetic diseases, including individualized medicine.