Management of Challenging Psoriasis Clinical Scenarios.

IF 3.5 3区 医学 Q1 DERMATOLOGY
Dermatology and Therapy Pub Date : 2025-06-01 Epub Date: 2025-04-15 DOI:10.1007/s13555-025-01393-3
Linda Stein Gold, Andrew Alexis, Brad P Glick, Mona Shahriari, Eingun James Song, Bruce Strober, Najat M Watch, Melodie Young
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引用次数: 0

Abstract

Psoriasis, a chronic inflammatory skin condition, can have a significant impact on patients' quality of life. Adoption of novel and emerging treatments has significantly improved psoriasis care in clinical practice, but challenges remain. The 'Bridging the Gaps in Challenging Psoriasis' meeting was held in October 2024 to discuss relevant evidence, knowledge gaps, and best practices pertaining to challenging presentations of psoriasis. This report captures important insights and practice impacting guidance gathered from the panel discussion on five topics. The meeting commenced with an in-depth discussion on managing psoriasis in high-impact areas (e.g., scalp, intertriginous regions, nails, and the palms and soles) followed by a discussion on the importance of identifying and addressing common comorbidities associated with psoriasis. The panel explored key considerations and unique challenges when treating psoriasis in patients with darker skin tones ('skin of color') and highlighted the need for tailored therapeutic approaches. A comprehensive dialogue ensued on strategies for managing primary and secondary treatment failures. The session concluded with a concise discussion on the future of psoriasis treatments and pharmacologic therapies currently being developed to manage psoriasis. While discussing various challenging psoriasis scenarios, the dermatology experts emphasized the need to approach psoriasis as a systemic disease and advocated for comprehensive management that addresses both the skin and the broader health of the patient.

具有挑战性的牛皮癣临床情况的管理。
牛皮癣是一种慢性炎症性皮肤病,会对患者的生活质量产生重大影响。采用新的和新兴的治疗已经显著改善牛皮癣护理在临床实践中,但挑战仍然存在。“弥合挑战性牛皮癣的差距”会议于2024年10月举行,讨论与牛皮癣挑战性表现相关的相关证据、知识差距和最佳实践。本报告从五个主题的小组讨论中收集了重要的见解和影响指导的实践。会议开始时,深入讨论了在高影响区域(如头皮、三叉区、指甲、手掌和脚底)管理牛皮癣的问题,随后讨论了识别和处理牛皮癣相关常见合并症的重要性。该小组探讨了在治疗深色皮肤(“有色皮肤”)患者的银屑病时的关键考虑因素和独特挑战,并强调了量身定制治疗方法的必要性。随后就管理初级和二级治疗失败的战略进行了全面对话。会议最后简要讨论了银屑病治疗的未来和目前正在开发的治疗银屑病的药物疗法。在讨论各种具有挑战性的牛皮癣情况时,皮肤科专家强调需要将牛皮癣作为一种全身性疾病来对待,并提倡对患者的皮肤和更广泛的健康进行综合管理。
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来源期刊
Dermatology and Therapy
Dermatology and Therapy Medicine-Dermatology
CiteScore
6.00
自引率
8.80%
发文量
187
审稿时长
6 weeks
期刊介绍: Dermatology and Therapy is an international, open access, peer-reviewed, rapid publication journal (peer review in 2 weeks, published 3–4 weeks from acceptance). The journal is dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of dermatological therapies. Studies relating to diagnosis, pharmacoeconomics, public health and epidemiology, quality of life, and patient care, management, and education are also encouraged. Areas of focus include, but are not limited to all clinical aspects of dermatology, such as skin pharmacology; skin development and aging; prevention, diagnosis, and management of skin disorders and melanomas; research into dermal structures and pathology; and all areas of aesthetic dermatology, including skin maintenance, dermatological surgery, and lasers. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/case series, trial protocols, and short communications. Dermatology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an International and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of quality research, which may be considered of insufficient interest by other journals. The journal appeals to a global audience and receives submissions from all over the world.
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