Antimicrobial resistance in bacteria from pig production chain: a systematic review and meta-analyses focused on the Brazilian context.

IF 7.3 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

Critical reviews in food science and nutrition Pub Date : 2025-04-13 DOI:10.1080/10408398.2025.2489531

Gracielle Rodrigues Pereira, Ana Beatriz Portes, Carlos Adam Conte, Marcelo Luiz Lima Brandão, Bernardete Ferraz Spisso

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引用次数: 0

Abstract

Pork industry plays an important role in antibiotics consumption, which can lead to antimicrobial resistance (AMR) spread. Hence, monitoring and controlling AMR in swine production chains is essential to reduce the risks to public health. A systematic review protocol was developed to assess AMR in the pig production chain in Brazil, the fourth largest producer and exporter of pork in the world. More than 3000 strains obtained from swine chain had their antibiotic resistance characteristics assessed. Results showed a major attention to the research of swine AMR in Salmonella and Escherichia coli. Resistance against quinolones has been most investigated and high levels of resistance against tetracyclines were observed. Moreover, resistance profiles and determinants against colistin were frequently found. Meta-analyses were performed to estimate the frequency of microorganisms from the World Health Organization (WHO) global priority pathogens list of antibiotic-resistant bacteria. The results showed prevalences ≤ 0.11 of each priority group in Brazilian pork. As far as is known, this is the first research to provide a comprehensive synthesis of available data on AMR in this production chain. It may support the tackling of knowledge gaps and inspire the enhancement of policies to monitoring, controlling, and managing foodborne AMR.

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猪生产链中细菌的抗菌素耐药性：一项针对巴西情况的系统综述和荟萃分析。

猪肉工业在抗生素消费中起着重要作用，这可能导致抗菌素耐药性（AMR）的传播。因此，监测和控制生猪生产链中的抗菌素耐药性对于减少对公众健康的风险至关重要。制定了一项系统审查方案，以评估巴西生猪生产链中的抗菌素耐药性。巴西是世界第四大猪肉生产国和出口国。对从猪链中获得的3000多株菌株进行了抗生素耐药特性评估。结果表明，沙门氏菌和大肠杆菌对猪耐药性的研究受到重视。对喹诺酮类药物的耐药性调查最多，并观察到对四环素的高水平耐药性。此外，经常发现对粘菌素的抗性概况和决定因素。进行荟萃分析以估计世界卫生组织（WHO）全球抗生素耐药细菌优先病原体清单中微生物的频率。结果表明，各优先组在巴西猪肉中的患病率≤0.11。就目前所知，这是第一次对这一生产链中抗菌素耐药性的现有数据进行全面综合的研究。它可能有助于解决知识差距，并激励加强监测、控制和管理食源性抗生素耐药性的政策。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Critical reviews in food science and nutrition 工程技术-食品科技

CiteScore

22.60

自引率

4.90%

发文量

600

审稿时长

7.5 months

期刊介绍： Critical Reviews in Food Science and Nutrition serves as an authoritative outlet for critical perspectives on contemporary technology, food science, and human nutrition. With a specific focus on issues of national significance, particularly for food scientists, nutritionists, and health professionals, the journal delves into nutrition, functional foods, food safety, and food science and technology. Research areas span diverse topics such as diet and disease, antioxidants, allergenicity, microbiological concerns, flavor chemistry, nutrient roles and bioavailability, pesticides, toxic chemicals and regulation, risk assessment, food safety, and emerging food products, ingredients, and technologies.