Regulating Effect of Weekend Catch-up Sleep on Association of Hepatic Steatosis with Atherosclerotic Cardiovascular Disease.

IF 1.9 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Balkan Medical Journal Pub Date : 2025-05-05 DOI:10.4274/balkanmedj.galenos.2025.2025-1-87

Yichuan Liu, Zongquan Wen, Nanrui Zeng

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引用次数: 0

Abstract

Background: Both insufficient and excessive catch-up sleep durations have been implicated in influencing the risk of cardiovascular diseases (CVDs) and metabolic disorders. However, the specific impact of weekend catch-up sleep (WCS) on the relationship between hepatic steatosis (HS) and atherosclerotic cardiovascular disease (ASCVD) remains unclear.

Aims: This cross-sectional study aims to examine the potential regulatory effect of WCS on the association between controlled attenuation parameter (CAP) and ASCVD.

Methods: Weighted logistic regression analyses were employed to evaluate the associations of CAP and WCS with ASCVD, expressed in terms of odds ratios (ORs) and 95% confidence intervals (CIs). The study also explored the effect of WCS on the CAP-ASCVD relationship and assessed the potential regulatory role of WCS in subgroups based on age, gender, body mass index, and obesity status.

Results: Eligible participants were categorized into two groups: those with an ASCVD risk < 7.5% (n = 1536) and those with an ASCVD risk ≥ 7.5% (n = 1612). After adjusting for covariates, CAP ≥ 274 dB/m was associated with a higher likelihood of ASCVD compared to the CAP < 274 dB/m (OR, 1.84, 95% CI, 1.24-2.73). When compared to a WCS duration of 0-1 hour, WCS ≥ 1 hour was found to increase the potential ASCVD risk associated with CAP (OR, 3.29, 95% CI, 1.41-7.68). Furthermore, among individuals with WCS ≥ 1 hour, CAP ≥ 274 dB/m was linked to a higher ASCVD risk than among those with CAP < 274 dB/m (OR, 3.72, 95% CI, 1.99-6.93). Additionally, in subgroups of participants aged ≥ 60 years, females, non-obese and obese individuals, WCS ≥ 1 hour was associated with an increased ASCVD risk related to CAP (all, p < 0.05).

Conclusion: A WCS duration of ≥ 1 hour may be associated with an increased ASCVD risk in adults with HS aged ≥ 40 years. However, further research is necessary to clarify the causal relationships between WCS, HS, and ASCVD.

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周末补觉对肝脂肪变性与动脉粥样硬化性心血管疾病的调节作用

背景：睡眠不足和睡眠过量都与心血管疾病（cvd）和代谢紊乱的风险有关。然而，周末补觉（WCS）对肝脂肪变性（HS）和动脉粥样硬化性心血管疾病（ASCVD）之间关系的具体影响尚不清楚。目的：本横断面研究旨在探讨WCS对控制衰减参数（CAP）与ASCVD之间关系的潜在调节作用。方法：采用加权logistic回归分析评估CAP和WCS与ASCVD的相关性，以比值比（ORs）和95%置信区间（ci）表示。该研究还探讨了WCS对CAP-ASCVD关系的影响，并评估了WCS在基于年龄、性别、体重指数和肥胖状况的亚组中的潜在调节作用。结果：符合条件的参与者被分为两组：ASCVD风险< 7.5% （n = 1536）和ASCVD风险≥7.5% （n = 1612）。在调整协变量后，与CAP < 274 dB/m相比，CAP≥274 dB/m与ASCVD的可能性更高（OR, 1.84, 95% CI, 1.24-2.73）。与WCS持续时间0-1小时相比，WCS≥1小时增加了与CAP相关的潜在ASCVD风险（OR, 3.29, 95% CI, 1.41-7.68）。此外，在WCS≥1小时的个体中，CAP≥274 dB/m的ASCVD风险高于CAP < 274 dB/m的个体（OR, 3.72, 95% CI, 1.99-6.93）。此外，在年龄≥60岁、女性、非肥胖和肥胖个体的亚组中，WCS≥1小时与CAP相关的ASCVD风险增加相关（均p < 0.05）。结论：在年龄≥40岁的HS患者中，WCS持续时间≥1小时可能与ASCVD风险增加相关。然而，WCS、HS和ASCVD之间的因果关系尚需进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Balkan Medical Journal MEDICINE, GENERAL & INTERNAL-

CiteScore

4.10

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： The Balkan Medical Journal (Balkan Med J) is a peer-reviewed open-access international journal that publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports and clinical images, invited reviews, editorials, letters, comments and letters to the Editor including reports on publication and research ethics. The journal is the official scientific publication of the Trakya University Faculty of Medicine, Edirne, Turkey and is printed six times a year, in January, March, May, July, September and November. The language of the journal is English. The journal is based on independent and unbiased double-blinded peer-reviewed principles. Only unpublished papers that are not under review for publication elsewhere can be submitted. Balkan Medical Journal does not accept multiple submission and duplicate submission even though the previous one was published in a different language. The authors are responsible for the scientific content of the material to be published. The Balkan Medical Journal reserves the right to request any research materials on which the paper is based. The Balkan Medical Journal encourages and enables academicians, researchers, specialists and primary care physicians of Balkan countries to publish their valuable research in all branches of medicine. The primary aim of the journal is to publish original articles with high scientific and ethical quality and serve as a good example of medical publications in the Balkans as well as in the World.