Burden to Partners of People with Psoriasis: Results from the FamilyPso International Study.

IF 8.6 1区医学 Q1 DERMATOLOGY

American Journal of Clinical Dermatology Pub Date : 2025-04-15 DOI:10.1007/s40257-025-00944-w

Ulrich Mrowietz, Crispin Meyer, Katja Großschädl, Wolfgang Weger, Peter Wolf, Melinda Gooderham, Ashley O'Toole, Ron Vender, Sascha Gerdes, Andreas Körber, Francesco Bellinato, Paolo Gisondi, Federico Bardazzi, Lidia Sacchelli, Corrado Zengarini, Esteban Dauden, Mar Llamas-Velasco, Cristina Santamaría, Teresa Abalde, Ángeles Flórez, Laura Salgado-Boquete, Emel Bulbul Baskan, Sezgi Sarikaya Solak, Armin Hartmann

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引用次数: 0

Abstract

Background: Psoriatic disease is a lifelong chronic illness for which there is no cure. It is well established that psoriasis leads to a major impairment of health-related quality-of-life and wellbeing. Most people with psoriasis live together with partners, bringing along a major burden for them. The FamilyPso was created to measure this burden in psoriasis.

Objective: The aim of the FamilyPso international study was to validate this tool and to show feasibility for the use of the FamilyPso across multiple countries.

Methods: A prospective cohort study was conducted in 11 centers in Austria, Canada, Germany, Italy, Spain, and Turkey. The factor structure of the FamiliyPso was examined by confirmatory factor analysis (CFA) including tests of measurement invariance for gender and language. Subgroups (e.g., countries and gender) were tested for significant differences, and the relationship between the severity of illness and FamilyPso scores was tested for differences between countries using a mixed regression model. Descriptive statistics for items and scores are presented herein.

Results: The cohort consisted of 556 people with psoriasis and their partners. Patients agreed that their partners would answer the questionnaire in their absence and return the forms to the centers. The mean age of patients and partners was 51 years. Psoriasis severity was mild in 57.6%, moderate in 31.5%, and severe in 10.9% of cases, and 91.3% received treatment. The results of the CFA confirmed the original factor structure with minor modifications. Self-assessed high severity of psoriasis was a predictor for a higher burden in 4/5 FamilyPso domains. There was an increased burden to partners related to the severity of psoriasis particularly in the domain "general emotional strain," including items such as a "feeling of helplessness." The results of the study showed that the FamilyPso could assess the burden of partners of people with psoriasis and can be used across different countries.

Conclusions: The data can improve management of psoriatic disease and should be considered in shared decision-making.

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牛皮癣患者伴侣的负担：来自FamilyPso国际研究的结果

背景：银屑病是一种无法治愈的终身慢性疾病。众所周知，牛皮癣导致与健康有关的生活质量和福祉的重大损害。大多数牛皮癣患者与伴侣生活在一起，这给他们带来了很大的负担。创建FamilyPso是为了测量牛皮癣患者的这种负担。目的：FamilyPso国际研究的目的是验证这一工具，并显示在多个国家使用FamilyPso的可行性。方法：在奥地利、加拿大、德国、意大利、西班牙和土耳其的11个中心进行前瞻性队列研究。familypso的因子结构采用验证性因子分析（CFA）进行检验，包括性别和语言的测量不变性检验。对亚组（如国家和性别）进行了重大差异测试，并使用混合回归模型测试了疾病严重程度与FamilyPso得分之间的关系，以确定国家之间的差异。本文给出了项目和分数的描述性统计。结果：该队列包括556名牛皮癣患者及其伴侣。患者同意他们的伴侣在他们不在时回答问卷，并将表格归还给中心。患者及其伴侣的平均年龄为51岁。银屑病严重程度为轻度的占57.6%，中度的占31.5%，重度的占10.9%，接受治疗的占91.3%。CFA的结果证实了原始因子结构，并进行了轻微的修改。自我评估的银屑病严重程度是4/5个FamilyPso域较高负担的预测因子。与牛皮癣的严重程度相关的伴侣负担增加，特别是在“一般情绪紧张”领域，包括“无助感”等项目。研究结果表明，FamilyPso可以评估牛皮癣患者伴侣的负担，并可在不同国家使用。结论：这些数据可以改善银屑病的治疗，在共同决策时应予以考虑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Clinical Dermatology 医学-皮肤病学

CiteScore

15.20

自引率

2.70%

发文量

审稿时长

>12 weeks

期刊介绍： The American Journal of Clinical Dermatology is dedicated to evidence-based therapy and effective patient management in dermatology. It publishes critical review articles and clinically focused original research covering comprehensive aspects of dermatological conditions. The journal enhances visibility and educational value through features like Key Points summaries, plain language summaries, and various digital elements, ensuring accessibility and depth for a diverse readership.