Micelle-Forming and Antimicrobial Properties of a Series of Bis-Quaternized Ammonium Compounds Based on DABCO Derivatives

IF 1.4 4区化学 Q4 CHEMISTRY, PHYSICAL

Colloid Journal Pub Date : 2025-05-14 DOI:10.1134/S1061933X25600010

Z. M. Shaihutdinova, A. S. Sapunova, D. V. Salakhieva, T. N. Pashirova, A. D. Voloshina, A. V. Bogdanov

引用次数: 0

Abstract

A set of methods (tensiometry, conductometry, dynamic light scattering, spectroscopy, and fluorimetry) has been employed to study the self-assembly of long-chain bis-quaternized hydroxyethyl group-containing derivatives of 1,4-diazabicyclo[2.2.2]octane. The critical micelle concentrations, adsorption characteristics of the air–water interface, solubilization capacities with respect to poorly water-soluble OrangeOT dye, aggregation numbers, and sizes of aggregates have been determined. The influence of the structure (alkyl chain length and head group charge) of the studied compounds on their micelle-forming and antimicrobial properties, as well as hemolytic activity, has been determined.

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一系列基于DABCO衍生物的双季铵盐化合物的胶束形成和抗菌性能

采用张力法、电导法、动态光散射法、光谱学和荧光法等方法研究了1,4-重氮双环[2.2.2]辛烷长链双季铵盐化羟乙基衍生物的自组装。测定了临界胶束浓度、空气-水界面的吸附特性、对难水溶性OrangeOT染料的增溶能力、聚集数和聚集物的大小。已经确定了所研究化合物的结构（烷基链长度和头基电荷）对其胶束形成和抗菌性能以及溶血活性的影响。

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来源期刊

Colloid Journal 化学-物理化学

CiteScore

2.20

自引率

18.20%

发文量

审稿时长

6-12 weeks

期刊介绍： Colloid Journal (Kolloidnyi Zhurnal) is the only journal in Russia that publishes the results of research in the area of chemical science dealing with the disperse state of matter and surface phenomena in disperse systems. The journal covers experimental and theoretical works on a great variety of colloid and surface phenomena: the structure and properties of interfaces; adsorption phenomena and structure of adsorption layers of surfactants; capillary phenomena; wetting films; wetting and spreading; and detergency. The formation of colloid systems, their molecular-kinetic and optical properties, surface forces, interaction of colloidal particles, stabilization, and criteria of stability loss of different disperse systems (lyosols and aerosols, suspensions, emulsions, foams, and micellar systems) are also topics of the journal. Colloid Journal also includes the phenomena of electro- and diffusiophoresis, electro- and thermoosmosis, and capillary and reverse osmosis, i.e., phenomena dealing with the existence of diffusion layers of molecules and ions in the vicinity of the interface.