Emile A. Bacha MD, Stephanie N. Nguyen MD, Andrew B. Goldstone MD, PhD, David Kalfa MD, PhD
{"title":"A Perspective on Neonatal Management of Hypoplastic Left Heart Syndrome","authors":"Emile A. Bacha MD, Stephanie N. Nguyen MD, Andrew B. Goldstone MD, PhD, David Kalfa MD, PhD","doi":"10.1053/j.pcsu.2024.12.002","DOIUrl":null,"url":null,"abstract":"<div><div>Hypoplastic left heart syndrome (HLHS)—a universally fatal condition only 40 years ago—remains one of the most challenging congenital heart defects. The advancements and insights gained from historical experiences with the Norwood operation have transformed the prognosis for HLHS patients and profoundly shaped contemporary outcomes. This progress has spurred continuous refinement of surgical techniques, transcatheter interventions, and perioperative care, leading to notable improvements in both survival rates and quality of life for HLHS patients. Herein, we focus on key historical lessons and their implications for future practices for neonatal management of HLHS.</div></div>","PeriodicalId":38774,"journal":{"name":"Pediatric Cardiac Surgery Annual","volume":"28 ","pages":"Pages 3-12"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Cardiac Surgery Annual","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1092912624000206","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Hypoplastic left heart syndrome (HLHS)—a universally fatal condition only 40 years ago—remains one of the most challenging congenital heart defects. The advancements and insights gained from historical experiences with the Norwood operation have transformed the prognosis for HLHS patients and profoundly shaped contemporary outcomes. This progress has spurred continuous refinement of surgical techniques, transcatheter interventions, and perioperative care, leading to notable improvements in both survival rates and quality of life for HLHS patients. Herein, we focus on key historical lessons and their implications for future practices for neonatal management of HLHS.
期刊介绍:
The Pediatric Cardiac Surgery Annual is a companion to Seminars in Thoracic and Cardiovascular Surgery . Together with the Seminars, the Annual provides complete coverage of the specialty by focusing on important developments in pediatric cardiac surgery. Each annual volume has an expert guest editor who invites prominent surgeons to review the areas of greatest change in pediatric cardiac surgery during the year. Topics include 1) Complete Atrioventricular Canal; 2) New Concepts of Cardiac Anatomy and Function -- The Helical Heart; 3) Valve Reconstruction (Replacement) in Congenital Heart Disease; 4) Evolving Developments in Congenital Heart Surgery.