Hepatitis B and C Screening and Linkage to Care in Migrants From Endemic Countries in Barcelona Through a Community Action

IF 6 2区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY
Anna Not, Hakima Ouaarab-Essadek, Marcos Montoro, Begoña Treviño, María Buti, Rosa M. Morillas, Antoni E. Bordoy, Cinta Folch, Xavier Majó, Jordi Casabona, Jordi Gómez i Prat, Elisa Martró
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Abstract

Background and Aims

Migrants from endemic areas are key populations for hepatitis B virus (HBV) and hepatitis C virus (HCV) infection screening in Europe. This study assessed the feasibility and outcomes of a community action that combined education, screening, and simplified access to care for migrants in Barcelona.

Methods

Adult migrants from Pakistan, Romania, and Senegal were included from 2021 to 2023, through a community action involving education, an epidemiological questionnaire, and rapid testing for HBV surface antigen (HBsAg) and HCV antibodies. If positive, DBS samples were collected for laboratory confirmation. Viremic cases were referred to an International Health Unit (IHU).

Results

Overall, 786 participants were included (346 from Pakistan, 304 from Senegal and 136 from Romania). Previous screening for HBV and HCV was 8.0% and 7.7%, respectively. HBsAg prevalence was 0.9% for migrants from Pakistan, 8.2% for those from Senegal and 1.4% for those from Romania (n = 30/786, 23 new diagnoses). Among these, 69.6% attended the IHU and were HBV-DNA positive, but none met treatment criteria. Anti-HCV prevalence was 3.5%, 0.7% and 1.4% for migrants from Pakistan, Senegal and Romania, respectively (n = 16/768, 12 new diagnoses), and HCV-RNA prevalence was 0.9%, 0.3% and 0.7%, respectively (N = 6, all new diagnoses); 4 (66.6%) cases were linked to treatment and two were cured.

Conclusions

This novel community action successfully reached migrants in a situation of vulnerability and provided them access to testing and care. The high prevalence observed and the limited self-knowledge of their HBV and HCV status justify targeted screening in these groups.

Abstract Image

通过社区行动在巴塞罗那从流行国家移民的乙型和丙型肝炎筛查和联系护理
背景和目的来自流行地区的移民是欧洲乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染筛查的关键人群。本研究评估了一项社区行动的可行性和结果,该行动将教育、筛查和简化巴塞罗那移民的护理机会结合起来。方法通过社区教育、流行病学问卷调查和快速检测HBV表面抗原(HBsAg)和HCV抗体,纳入2021年至2023年来自巴基斯坦、罗马尼亚和塞内加尔的成年移民。如果呈阳性,则采集脑起搏器样本进行实验室确认。病毒血症病例被转介到国际卫生单位。结果共纳入786名参与者(346名来自巴基斯坦,304名来自塞内加尔,136名来自罗马尼亚)。既往HBV和HCV筛查率分别为8.0%和7.7%。来自巴基斯坦移民的HBsAg患病率为0.9%,来自塞内加尔的为8.2%,来自罗马尼亚的为1.4% (n = 30/ 786,23例新诊断)。其中69.6%的人参加了IHU, HBV-DNA阳性,但没有人符合治疗标准。巴基斯坦、塞内加尔和罗马尼亚移民的抗- hcv患病率分别为3.5%、0.7%和1.4% (n = 16/768, 12例新诊断),HCV-RNA患病率分别为0.9%、0.3%和0.7% (n = 6,均为新诊断);治疗成功4例(66.6%),治愈2例。这一新颖的社区行动成功地触及了处于弱势地位的移民,并为他们提供了检测和护理的机会。观察到的高患病率和对HBV和HCV状况的有限自我认识证明了对这些群体进行针对性筛查的理由。
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来源期刊
Liver International
Liver International 医学-胃肠肝病学
CiteScore
13.90
自引率
4.50%
发文量
348
审稿时长
2 months
期刊介绍: Liver International promotes all aspects of the science of hepatology from basic research to applied clinical studies. Providing an international forum for the publication of high-quality original research in hepatology, it is an essential resource for everyone working on normal and abnormal structure and function in the liver and its constituent cells, including clinicians and basic scientists involved in the multi-disciplinary field of hepatology. The journal welcomes articles from all fields of hepatology, which may be published as original articles, brief definitive reports, reviews, mini-reviews, images in hepatology and letters to the Editor.
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