Thin air, thick blood: High altitude trauma centers have increased deep venous thrombosis rates

IF 2.7 3区医学 Q1 SURGERY

American journal of surgery Pub Date : 2025-05-07 DOI:10.1016/j.amjsurg.2025.116365

Franklin L. Wright , Thomas J. Schroeppel , Michael R. Bronsert , Shane Urban , Stephanie A. Vega , Michael W. Cripps , Warren C. Dorlac , Whitney R. Jenson , Jennifer E. Baker , Robert C. McIntyre Jr.

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引用次数: 0

Abstract

Background

Patients undergoing elective procedures at altitudes >4000 ft have higher deep venous thrombosis (DVT) rates compared to those performed at ≤ 1000 ft.

Design

We reviewed the American College of Surgeons Trauma Quality Improvement Program (TQIP) database from 2014 to 2019. Adults are divided into LOW (<1001 ft) or HIGH (>4000 ft) altitude treatment with DVT rates compared by multivariable regression analysis as well as using a 2:1 propensity matched model.

Results

Risk-adjusted odds ratio (OR) for DVT at high altitude was 1.53 [95 % CI 1.42–1.64]. In patients with an Injury Severity Score (ISS) ≥ 16, the DVT rate was 1.10 % (LOW) vs 1.59 % (HIGH); risk-adjusted OR for DVT at high altitude with ISS ≥ 16 was 1.67 [1.53–1.83]. Under the propensity matched model, DVT rates at higher altitude had an OR of 1.59 [1.46–1.74].

Conclusion

Following traumatic injury, DVT rates are increased in higher altitude treatment facilities compared to their low elevation peers.

Abstract Image

查看原文本刊更多论文

空气稀薄，血液粘稠：高海拔创伤中心深静脉血栓发生率增高

背景：与海拔≤1000英尺的患者相比，在海拔4000英尺处接受选择性手术的患者深静脉血栓（DVT）发生率更高。设计：我们回顾了2014年至2019年美国外科医师学会创伤质量改善计划（TQIP）数据库。通过多变量回归分析和2:1倾向匹配模型，将成人分为低海拔（<；1001英尺）和高海拔（>；4000英尺）两组，比较DVT发生率。结果高海拔地区DVT的风险校正优势比（OR）为1.53 [95% CI 1.42-1.64]。在损伤严重程度评分(ISS)≥16的患者中，DVT发生率为1.10% (LOW) vs 1.59% (HIGH)；ISS≥16的高海拔DVT风险调整OR为1.67[1.53-1.83]。倾向匹配模型下，高海拔地区DVT发生率OR为1.59[1.46-1.74]。结论创伤后，高海拔治疗设施的DVT发生率高于低海拔治疗设施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American journal of surgery 医学-外科

CiteScore

5.00

自引率

6.70%

发文量

570

审稿时长

56 days

期刊介绍： The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.