{"title":"Association of neuromuscular reversal drug with postoperative pulmonary complications in bronchoscopy: definitional challenges.","authors":"Douglas A Colquhoun,Ana Fernandez-Bustamante","doi":"10.1016/j.bja.2025.04.005","DOIUrl":null,"url":null,"abstract":"A recent retrospective study examined a composite of postoperative pulmonary complications after neostigmine or sugammadex for reversal of neuromuscular block in patients undergoing interventional pulmonology and bronchoscopic procedures. This study reviewed the electronic medical records of 8557 patients across hospitals within a single health system, finding an increased risk of a composite of postoperative pulmonary complications in those receiving sugammadex (odds ratio 1.44; 95% confidence interval: 1.02-2.05). We discuss the challenge of interpreting conflicting findings in the contemporary perioperative literature arising from heterogeneous definitions of postoperative pulmonary complications.","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"50 1","pages":""},"PeriodicalIF":9.1000,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"British journal of anaesthesia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.bja.2025.04.005","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
A recent retrospective study examined a composite of postoperative pulmonary complications after neostigmine or sugammadex for reversal of neuromuscular block in patients undergoing interventional pulmonology and bronchoscopic procedures. This study reviewed the electronic medical records of 8557 patients across hospitals within a single health system, finding an increased risk of a composite of postoperative pulmonary complications in those receiving sugammadex (odds ratio 1.44; 95% confidence interval: 1.02-2.05). We discuss the challenge of interpreting conflicting findings in the contemporary perioperative literature arising from heterogeneous definitions of postoperative pulmonary complications.
期刊介绍:
The British Journal of Anaesthesia (BJA) is a prestigious publication that covers a wide range of topics in anaesthesia, critical care medicine, pain medicine, and perioperative medicine. It aims to disseminate high-impact original research, spanning fundamental, translational, and clinical sciences, as well as clinical practice, technology, education, and training. Additionally, the journal features review articles, notable case reports, correspondence, and special articles that appeal to a broader audience.
The BJA is proudly associated with The Royal College of Anaesthetists, The College of Anaesthesiologists of Ireland, and The Hong Kong College of Anaesthesiologists. This partnership provides members of these esteemed institutions with access to not only the BJA but also its sister publication, BJA Education. It is essential to note that both journals maintain their editorial independence.
Overall, the BJA offers a diverse and comprehensive platform for anaesthetists, critical care physicians, pain specialists, and perioperative medicine practitioners to contribute and stay updated with the latest advancements in their respective fields.