Is Intravenous Contrast Associated with Increased Risk of Acute Kidney Injury?

IF 1.2 4区医学 Q3 EMERGENCY MEDICINE

Journal of Emergency Medicine Pub Date : 2025-05-01 DOI:10.1016/j.jemermed.2024.11.013

Brit Long MD , Samuel M. Keim MD, MS , Michael Gottlieb MD , Steven G. Schauer DO, MS , Gillian Schmitz MD

引用次数: 0

Abstract

Background

Computed tomography (CT) is a common imaging modality used in the emergency department. Intravenous (i.v.) contrast can assist with visualization of pathology, particularly for inflammatory conditions and vascular structures. However, i.v. contrast has historically been associated with the risk of acute kidney injury (AKI).

Clinical Question

Is i.v. contrast associated with an increased risk of AKI?

Evidence Review

Studies retrieved included four systematic reviews and meta-analyses evaluating the use of i.v. contrast for CT and association with AKI, need for kidney replacement therapy, and mortality. These studies provide estimates of the potential association of AKI with use of i.v. contrast for CT.

Conclusion

Based upon the available literature, the use of i.v. contrast for CT imaging does not seem to be associated with an increased risk of AKI.

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静脉造影剂与急性肾损伤风险增加有关吗？

背景计算机断层扫描（CT）是急诊科常用的成像方式。静脉造影剂可以帮助病理可视化，特别是炎症和血管结构。然而，静脉注射造影剂历来与急性肾损伤（AKI）的风险相关。静脉注射造影剂与AKI风险增加有关吗？证据综述：检索到的研究包括四项系统综述和荟萃分析，评估CT静脉造影剂的使用与AKI的关系、肾脏替代治疗的需要和死亡率。这些研究提供了AKI与使用CT静脉造影剂的潜在关联的估计。结论根据现有文献，使用静脉造影剂进行CT成像似乎与AKI风险增加无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Emergency Medicine 医学-急救医学

CiteScore

2.40

自引率

6.70%

发文量

339

审稿时长

2-4 weeks

期刊介绍： The Journal of Emergency Medicine is an international, peer-reviewed publication featuring original contributions of interest to both the academic and practicing emergency physician. JEM, published monthly, contains research papers and clinical studies as well as articles focusing on the training of emergency physicians and on the practice of emergency medicine. The Journal features the following sections: • Original Contributions • Clinical Communications: Pediatric, Adult, OB/GYN • Selected Topics: Toxicology, Prehospital Care, The Difficult Airway, Aeromedical Emergencies, Disaster Medicine, Cardiology Commentary, Emergency Radiology, Critical Care, Sports Medicine, Wound Care • Techniques and Procedures • Technical Tips • Clinical Laboratory in Emergency Medicine • Pharmacology in Emergency Medicine • Case Presentations of the Harvard Emergency Medicine Residency • Visual Diagnosis in Emergency Medicine • Medical Classics • Emergency Forum • Editorial(s) • Letters to the Editor • Education • Administration of Emergency Medicine • International Emergency Medicine • Computers in Emergency Medicine • Violence: Recognition, Management, and Prevention • Ethics • Humanities and Medicine • American Academy of Emergency Medicine • AAEM Medical Student Forum • Book and Other Media Reviews • Calendar of Events • Abstracts • Trauma Reports • Ultrasound in Emergency Medicine