Correction to “Sequential Assembly of Cell-Laden Hydrogel Constructs to Engineer Vascular-Like Microchannels”

IF 3.5 2区 生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Yanan Du, Majid Ghodousi, Hao Qi, Nikhil Haas, Wenqian Xiao, Ali Khademhosseini
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引用次数: 0

Abstract

In the published article, the images in Figure 4B,D were found to be from the same sample that was sequentially exposed to different conditions and analyzed. The authors have data from an independent experiment in which the gels were not sequentially analyzed (Figure 4 below). The updated figure does not alter the interpretation of the data or the conclusions of the study. We apologize for any inconvenience.

Abstract Image
Figure 4
Open in figure viewerPowerPoint
Viability tests for the cell-laden tubular hydrogels as a function of the steps in the assembly process. The sequential assembly procedure was shown to be cell-friendly as demonstrated by viability tests for: (A) 3T3 fibroblast-laden microgels. (B) Microgels washed three times with photoinitiator (PI) (1% in DPBS). (C) Microgels exposed to oil. (D) Microgels exposed to both PI and oil. (E) Microgel assembly after 2 days in culture medium. (F) Quantification of samples (n = 3) after each fabrication step showed that the assembly process did not result in a significant loss of cell viability. Scale bar: 500 µm.
更正“装载细胞的水凝胶结构的顺序组装以工程血管样微通道”
在已发表的文章中,我们发现图4B、D中的图像来自同一样品,并对其进行了顺序暴露于不同条件下的分析。作者有一个独立实验的数据,其中凝胶没有被顺序分析(图4)。更新后的数据不会改变对数据的解释或研究的结论。给您带来的不便,我们深表歉意。图4在图查看器中打开powerpoint负载细胞的管状水凝胶的活力测试作为组装过程中步骤的函数。顺序组装过程被证明是细胞友好的,正如活力测试所证明的:(A) 3T3负载成纤维细胞的微凝胶。(B)微凝胶用光引发剂(PI) (1% DPBS)洗涤三次。(C)暴露于油中的微凝胶。(D)同时暴露于PI和油中的微凝胶。(E)培养基中2天后的微凝胶组装。(F)每个制备步骤后对样品(n = 3)的定量分析表明,装配过程不会导致细胞活力的显著丧失。比例尺:500µm。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biotechnology and Bioengineering
Biotechnology and Bioengineering 工程技术-生物工程与应用微生物
CiteScore
7.90
自引率
5.30%
发文量
280
审稿时长
2.1 months
期刊介绍: Biotechnology & Bioengineering publishes Perspectives, Articles, Reviews, Mini-Reviews, and Communications to the Editor that embrace all aspects of biotechnology. These include: -Enzyme systems and their applications, including enzyme reactors, purification, and applied aspects of protein engineering -Animal-cell biotechnology, including media development -Applied aspects of cellular physiology, metabolism, and energetics -Biocatalysis and applied enzymology, including enzyme reactors, protein engineering, and nanobiotechnology -Biothermodynamics -Biofuels, including biomass and renewable resource engineering -Biomaterials, including delivery systems and materials for tissue engineering -Bioprocess engineering, including kinetics and modeling of biological systems, transport phenomena in bioreactors, bioreactor design, monitoring, and control -Biosensors and instrumentation -Computational and systems biology, including bioinformatics and genomic/proteomic studies -Environmental biotechnology, including biofilms, algal systems, and bioremediation -Metabolic and cellular engineering -Plant-cell biotechnology -Spectroscopic and other analytical techniques for biotechnological applications -Synthetic biology -Tissue engineering, stem-cell bioengineering, regenerative medicine, gene therapy and delivery systems The editors will consider papers for publication based on novelty, their immediate or future impact on biotechnological processes, and their contribution to the advancement of biochemical engineering science. Submission of papers dealing with routine aspects of bioprocessing, description of established equipment, and routine applications of established methodologies (e.g., control strategies, modeling, experimental methods) is discouraged. Theoretical papers will be judged based on the novelty of the approach and their potential impact, or on their novel capability to predict and elucidate experimental observations.
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