Nanosecond-pulsed laser ablation synthesis of gold nanoparticles in DDDW, NaOH, and DMEM liquid media: unveiling of microstructural morphological, chemical, optical, and structural characterizations and cytotoxic evaluation of enhanced anticancer efficacy

Abstract

Synthesis of gold nanoparticles (AuNPs) in the presence of three different liquid mediums was carried out using ns-pulsed laser ablation in liquid: DDDW, NaOH, and DMEM. X-ray diffraction (XRD), atomic force microscopy (AFM), transmission electron microscopic investigations (TEM), Fourier transform infrared (FTIR), and UV–visible spectroscopy were some of the techniques that were utilized in order to describe the structural, chemical, morphological, topological, and optical features of as-produced nanomaterials. The characterization studies provided evidence that the successful synthesis route was appropriate. It has been demonstrated via the utilization of cytotoxicity tests that gold nanoparticles have the capacity to not only eradicate cancer cells but also stop their reproduction. This ability was demonstrated by gold nanoparticles. The Au nanoparticles showed an extraordinarily deadly efficacy against cancer cells as compared to cancer cells that had not been treated with the chemical. This was accomplished by preventing the growth and reproduction of cancer cells.