Hyunjae Kim, Hyeon Hwang, Jiwoo Lee, Sihyeon Park, Dain Kim, Taewhoo Lee, Chanwoong Yoon, Jiwoong Sohn, Jungwoo Park, Olga Reykhart, Thomas Fetherston, Donghee Choi, Soo Heon Kwak, Qingyu Chen, Jaewoo Kang
{"title":"Small language models learn enhanced reasoning skills from medical textbooks","authors":"Hyunjae Kim, Hyeon Hwang, Jiwoo Lee, Sihyeon Park, Dain Kim, Taewhoo Lee, Chanwoong Yoon, Jiwoong Sohn, Jungwoo Park, Olga Reykhart, Thomas Fetherston, Donghee Choi, Soo Heon Kwak, Qingyu Chen, Jaewoo Kang","doi":"10.1038/s41746-025-01653-8","DOIUrl":null,"url":null,"abstract":"<p>Small language models (SLM) offer promise for medical applications by addressing the privacy and hardware constraints of large language models; however, their limited parameters (often fewer than ten billion) hinder multi-step reasoning for complex medical tasks. This study presents Meerkat, a new family of medical SLMs designed to be lightweight while enhancing reasoning capabilities. We begin by designing an effective and efficient training method. This involves extracting high-quality chain-of-thought reasoning paths from 18 medical textbooks, which are then combined with diverse instruction-following datasets within the medical domain, totaling 441K training examples. Fine-tuning was conducted on open-source SLMs using this curated dataset. Our Meerkat-7B and Meerkat-8B models outperformed their counterparts by 22.3% and 10.6% across six exam datasets, respectively. They also improved scores on the NEJM Case Challenge from 7 to 16 and from 13 to 20, surpassing the human score of 13.7. Additionally, they demonstrated superiority in expert evaluations, excelling in all metrics—completeness, factuality, clarity, and logical consistency—of reasoning abilities.</p>","PeriodicalId":19349,"journal":{"name":"NPJ Digital Medicine","volume":"34 1","pages":""},"PeriodicalIF":12.4000,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"NPJ Digital Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41746-025-01653-8","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Small language models (SLM) offer promise for medical applications by addressing the privacy and hardware constraints of large language models; however, their limited parameters (often fewer than ten billion) hinder multi-step reasoning for complex medical tasks. This study presents Meerkat, a new family of medical SLMs designed to be lightweight while enhancing reasoning capabilities. We begin by designing an effective and efficient training method. This involves extracting high-quality chain-of-thought reasoning paths from 18 medical textbooks, which are then combined with diverse instruction-following datasets within the medical domain, totaling 441K training examples. Fine-tuning was conducted on open-source SLMs using this curated dataset. Our Meerkat-7B and Meerkat-8B models outperformed their counterparts by 22.3% and 10.6% across six exam datasets, respectively. They also improved scores on the NEJM Case Challenge from 7 to 16 and from 13 to 20, surpassing the human score of 13.7. Additionally, they demonstrated superiority in expert evaluations, excelling in all metrics—completeness, factuality, clarity, and logical consistency—of reasoning abilities.
期刊介绍:
npj Digital Medicine is an online open-access journal that focuses on publishing peer-reviewed research in the field of digital medicine. The journal covers various aspects of digital medicine, including the application and implementation of digital and mobile technologies in clinical settings, virtual healthcare, and the use of artificial intelligence and informatics.
The primary goal of the journal is to support innovation and the advancement of healthcare through the integration of new digital and mobile technologies. When determining if a manuscript is suitable for publication, the journal considers four important criteria: novelty, clinical relevance, scientific rigor, and digital innovation.