Case report:Acute hepatic and renal failure caused by alcohol and acetaminophen poisoning

Abstract

Background

Acetaminophen, a commonly used antipyretic and analgesic in clinical practice, is widely applied due to its effectiveness in relieving pain and reducing fever, as well as its low gastrointestinal irritation. However, taking large doses or using it long - term, taking it while drinking alcohol, or taking two or more drugs containing acetaminophen can lead to severe drug - induced liver damage, and in rare cases, kidney function damage and even death.

Case

This article reports a case of a young female patient who experienced coma after excessive alcohol consumption and overdose of acetaminophen due to emotional breakdown. After rescue, the patient concealed her medication history and left the hospital on her own after regaining consciousness. Six days later, the patient was re - admitted due to coagulation disorders, and it was found that she had severe acute hepatic and renal function damage. After a clear diagnosis through toxicological analysis, the patient received active treatment and recovered.

Why should an emergency physician be aware of this?

Combining with literature reports, this article analyzes the phenomenon of young female patients attempting suicide by taking acetaminophen while drinking heavily in an emotionally out - of - control state, and explores the mechanism of liver and kidney function damage caused by excessive use of acetaminophen, aiming to draw the attention of clinicians and society.