Javier Zorrilla Abad , Débora Sanz Álvarez , Gema Manrique Martín , Laura Herrera Castillo , Jesús López-Herce Cid , Grupo de Código Ictus Pediátrico
{"title":"Ictus en cuidados intensivos pediátricos","authors":"Javier Zorrilla Abad , Débora Sanz Álvarez , Gema Manrique Martín , Laura Herrera Castillo , Jesús López-Herce Cid , Grupo de Código Ictus Pediátrico","doi":"10.1016/j.medin.2025.502154","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>To analyze the frequency, causes, risk factors, mortality and sequelae of stroke in children admitted to the pediatric intensive care unit (PICU).</div></div><div><h3>Design</h3><div>Single-center retrospective observational study based on a prospective database.</div></div><div><h3>Setting</h3><div>Pediatric intensive care unit.</div></div><div><h3>Patients</h3><div>Children between one month and eighteen years of age admitted to the PICU and diagnosed with stroke were included.</div></div><div><h3>Main variables of interest</h3><div>Epidemiological, clinical, diagnostic and treatment data, sequelae and mortality were recorded.</div></div><div><h3>Interventions</h3><div>None.</div></div><div><h3>Results</h3><div>46 patients were studied, of whom 29 (63%) had an ischemic stroke, 14 (30.4%) a hemorrhagic stroke, 1 (2.2%) venous sinus thrombosis and 2 (4.3%) mixed stroke. 11 patients (23.9%) had heart disease and 7 (15.2%) were treated with extracorporeal membrane oxygenation (ECMO) or ventricular assist. 8.6% of patients were treated with fibrinolysis or thrombectomy. 9 patients (19.6%) died. Patients with heart disease and those treated with ECMO had a higher mortality rate. 23 children, 62.1% of survivors, suffered sequelae at discharge. The most frequent sequelae were hemiparesis. Sequelae were significantly more frequent in patients who presented with motor symptoms (76.2%) (<em>P</em> <!--><<!--> <!-->.001).</div></div><div><h3>Conclusions</h3><div>The frequency of ischemic stroke in pediatric patients is higher than that of hemorrhagic stroke. Pediatric patients who suffer a stroke have a high mortality rate and a high rate of sequelae. Patients with heart disease and those treated with ECMO are those who present stroke most frequently and have a higher mortality rate.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 5","pages":"Article 502154"},"PeriodicalIF":2.7000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina Intensiva","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0210569125000178","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives
To analyze the frequency, causes, risk factors, mortality and sequelae of stroke in children admitted to the pediatric intensive care unit (PICU).
Design
Single-center retrospective observational study based on a prospective database.
Setting
Pediatric intensive care unit.
Patients
Children between one month and eighteen years of age admitted to the PICU and diagnosed with stroke were included.
Main variables of interest
Epidemiological, clinical, diagnostic and treatment data, sequelae and mortality were recorded.
Interventions
None.
Results
46 patients were studied, of whom 29 (63%) had an ischemic stroke, 14 (30.4%) a hemorrhagic stroke, 1 (2.2%) venous sinus thrombosis and 2 (4.3%) mixed stroke. 11 patients (23.9%) had heart disease and 7 (15.2%) were treated with extracorporeal membrane oxygenation (ECMO) or ventricular assist. 8.6% of patients were treated with fibrinolysis or thrombectomy. 9 patients (19.6%) died. Patients with heart disease and those treated with ECMO had a higher mortality rate. 23 children, 62.1% of survivors, suffered sequelae at discharge. The most frequent sequelae were hemiparesis. Sequelae were significantly more frequent in patients who presented with motor symptoms (76.2%) (P < .001).
Conclusions
The frequency of ischemic stroke in pediatric patients is higher than that of hemorrhagic stroke. Pediatric patients who suffer a stroke have a high mortality rate and a high rate of sequelae. Patients with heart disease and those treated with ECMO are those who present stroke most frequently and have a higher mortality rate.
期刊介绍:
Medicina Intensiva is the journal of the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC) and of Pan American and Iberian Federation of Societies of Intensive and Critical Care Medicine. Medicina Intensiva has become the reference publication in Spanish in its field. The journal mainly publishes Original Articles, Reviews, Clinical Notes, Consensus Documents, Images, and other information relevant to the specialty. All works go through a rigorous selection process. The journal accepts submissions of articles in English and in Spanish languages. The journal follows the publication requirements of the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE).