ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI)

Blood Vessels, Thrombosis & Hemostasis Pub Date : 2025-05-01 DOI:10.1016/j.bvth.2025.100064

Jerrold H. Levy , Peta M. A. Alexander , Alisa S. Wolberg , Owen J. T. McCarty , Anthony E. Pusateri , Raquel R. Bartz , Wolfgang Bergmeier , Mitchell J. Cohen , Jean M. Connors , James H. Morrissey , Matthew D. Neal , Elisabeth T. Tracy , Keith McCrae , Bruce A. Sullenger

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Abstract

In May 2024, the Division of Blood Diseases and Resources of the National Heart, Lung, and Blood Institute (NHLBI) hosted a hybrid workshop on “Extracorporeal membrane oxygenation (ECMO)-induced coagulopathy: strategic initiatives for research and clinical practice.” The event brought together clinicians, scientists, bioengineers, and policymakers to address the challenges of ECMO-associated coagulopathy and explore novel therapeutic approaches. Through expert presentations and collaborative discussions, the workshop focused on innovative anticoagulation strategies, precision medicine, and advanced diagnostics to enhance patient care. The discussions also identified critical research gaps and opportunities for future interdisciplinary collaboration. This summary reviews the current state of knowledge and outlines future research directions for improving ECMO-induced coagulopathy management.

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ecmo诱导的凝血病：研究和临床实践的战略举措（NHLBI研讨会报告）

2024年5月，国家心肺血液研究所（NHLBI）血液疾病和资源部门举办了一场关于“体外膜氧合（ECMO）诱导的凝血病：研究和临床实践的战略举措”的混合研讨会。该会议汇集了临床医生、科学家、生物工程师和政策制定者，共同应对ecmo相关凝血病的挑战，并探索新的治疗方法。通过专家报告和合作讨论，研讨会重点讨论了创新抗凝策略、精准医疗和先进诊断以加强患者护理。讨论还确定了关键的研究差距和未来跨学科合作的机会。本文综述了目前的知识状况，并概述了改善ecmo诱导的凝血病管理的未来研究方向。

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Blood Vessels, Thrombosis & Hemostasis

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