P122 Comparative study between DAS28-CRP and SDAI in assessing rheumatoid arthritis activity

Abstract

Background/Aims The choice between different indices for assessing disease activity in rheumatoid arthritis (RA) is often challenging due to the highly heterogeneous clinical presentation. The objective of our study was to assess the level of similarity between the SDAI (Simplified Disease Activity Index) and DAS28-CRP (Disease Activity Score using C-reactive protein) in evaluating RA activity. Methods In this cross-sectional study, a total of 183 patients diagnosed with RA according to the ACR/EULAR 2009 criteria were included. The correlation between the two indices was assessed using Pearson’s correlation coefficient (r), and the similarity between these two scores was evaluated with Kendall’s tau coefficient (K). Results The female-to-male ratio was 9:1, and the average age was 58.54 ± 12.23 years. Seropositivity and joint deformity were present in 87% and 69% of the patients, respectively. The mean DAS28-CRP score was 4.69 ± 1.43 [1.6-7.7], and the mean SDAI score was 29.62 ± 14.04 [2.5-66]. A strong and statistically significant positive correlation was observed between the DAS28-CRP and SDAI indices (p = 0.000). The DAS28-CRP categorized patients into the same disease activity category as the SDAI in 88% of cases. Specifically, 68% of patients had active RA according to both DAS28-CRP and SDAI, and 20% were in remission based on both scores. A discrepancy between the two scores was observed in only 12% of patients. Conclusion Our study demonstrated a high level of concordance between the SDAI and DAS28-CRP scores. In daily practice, DAS28 remains the most widely used index. However, our results suggest that SDAI should be used more frequently due to its reproducibility and inclusion of a physician’s global assessment of RA activity. Disclosure M. Jnyah: None. I. El Mezouar: None. N. Akasbi: None. T. Harzy: None.