FADE: Forecasting for anomaly detection on ECG

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Paula Ruiz-Barroso , Francisco M. Castro , José Miranda , Denisa-Andreea Constantinescu , David Atienza , Nicolás Guil
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引用次数: 0

Abstract

Background and Objective:

Cardiovascular diseases, a leading cause of noncommunicable disease-related deaths, require early and accurate detection to improve patient outcomes. Taking advantage of advances in machine learning and deep learning, multiple approaches have been proposed in the literature to address the challenge of detecting ECG anomalies. Typically, these methods are based on the manual interpretation of ECG signals, which is time consuming and depends on the expertise of healthcare professionals. The objective of this work is to propose a deep learning system, FADE, designed for normal ECG forecasting and anomaly detection, which reduces the need for extensive labeled datasets and manual interpretation.

Methods:

We propose FADE, a deep learning system designed for normal ECG forecasting, trained in a self-supervised manner with a novel morphological inspired loss function, that can be used for anomaly detection. Unlike conventional models that learn from labeled anomalous ECG waveforms, our approach predicts the future of normal ECG signals, thus avoiding the need for extensive labeled datasets. Using a novel distance function to compare forecasted ECG signals with actual sensor data, our method effectively identifies cardiac anomalies. Additionally, this approach can be adapted to new contexts (e.g., different sensors, patients, etc.) through domain adaptation techniques. To evaluate our proposal, we performed a set of experiments using two publicly available datasets: MIT-BIH NSR and MIT-BIH Arrythmia.

Results:

The results demonstrate that our system achieves an average accuracy of 83.84% in anomaly detection, while correctly classifying normal ECG signals with an accuracy of 85.46%.

Conclusions:

Our proposed approach exhibited superior performance in the early detection of cardiac anomalies in ECG signals, surpassing previous methods that predominantly identify a limited range of anomalies. FADE effectively detects both abnormal heartbeats and arrhythmias, offering significant advantages in healthcare through cost reduction, facilitation of remote monitoring, and efficient processing of large-scale ECG data.
用于心电异常检测的预测
背景和目的:心血管疾病是导致非传染性疾病相关死亡的主要原因,需要及早、准确地发现以改善患者预后。利用机器学习和深度学习的进步,文献中提出了多种方法来解决检测ECG异常的挑战。通常,这些方法都是基于人工解读ECG信号,这既耗时又依赖于医疗保健专业人员的专业知识。这项工作的目的是提出一个深度学习系统,FADE,专为正常心电图预测和异常检测而设计,减少了对大量标记数据集和人工解释的需求。方法:我们提出了一种名为FADE的深度学习系统,该系统以自监督的方式训练,具有新颖的形态启发损失函数,可用于异常检测。与从标记异常心电波形中学习的传统模型不同,我们的方法预测了正常心电信号的未来,从而避免了对大量标记数据集的需要。利用一种新颖的距离函数来比较预测的心电信号与实际传感器数据,我们的方法有效地识别心脏异常。此外,这种方法可以通过领域适应技术适应新的环境(例如,不同的传感器,患者等)。为了评估我们的建议,我们使用两个公开可用的数据集进行了一组实验:MIT-BIH NSR和MIT-BIH心律失常。结果:系统异常检测的平均准确率为83.84%,对正常心电信号的正确分类准确率为85.46%。结论:我们提出的方法在ECG信号中早期检测心脏异常方面表现优异,超越了以前主要识别有限范围异常的方法。通过降低成本、促进远程监测和高效处理大规模心电数据,FADE可以有效地检测异常心跳和心律失常,在医疗保健领域具有显著优势。
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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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