Optimizing Treatment: The Role of Pharmacology, Genomics, and AI in Improving Patient Outcomes

IF 3.5 4区 医学 Q2 CHEMISTRY, MEDICINAL
Fazil Ahmad
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Abstract

Recent advances in pharmacology are revolutionizing drug discovery and treatment strategies through personalized medicine, pharmacogenomics, and artificial intelligence (AI). The objective of the present study is to review the role of personalized medicine, pharmacogenomics, and AI-based strategies in optimizing patient outcomes with improved drug efficacy and reduced side effects. A comprehensive review was performed to debate the utility of pharmacogenomics in the prediction of drug response, the role of AI in drug discovery, and the utility of personalized medicine in the clinic. This review highlights how drug discovery and treatment techniques are evolving with the aid of personalized medicine, pharmacogenomics, and AI. Personalized medicine makes the treatment fit the DNA pattern for higher efficacy and minimal side effects. Pharmacogenomics forecasts the action of a drug in terms of genetic difference. AI speeds up drug discovery to enhance the effectiveness and accuracy of finding and evaluating drug leads. Studies show that customized medicine charts therapy to an individual patient's individual genetic profile, resulting in better therapy. Pharmacogenomics facilitates precise drug selection by considering genetic variations, reducing adverse reactions. AI speeds up drug discovery by applying predictive modeling and data-driven evaluation to propel optimized drug development pathways. Together, these advances are enabling more efficient and safer treatment practices across medical disciplines. The combination of pharmacology, genomics, and AI is revolutionizing contemporary healthcare through the personalization of treatments, improved drug safety, and therapeutic outcomes. The future of research should be on optimizing these techniques and overcoming ethical and regulatory issues to facilitate broader clinical implementation.

优化治疗:药理学、基因组学和人工智能在改善患者预后中的作用
药理学的最新进展正在通过个性化医疗、药物基因组学和人工智能(AI)彻底改变药物发现和治疗策略。本研究的目的是回顾个性化医疗、药物基因组学和基于人工智能的策略在优化患者预后、提高药物疗效和减少副作用方面的作用。本文对药物基因组学在药物反应预测中的应用、人工智能在药物发现中的作用以及个性化医疗在临床中的应用进行了全面的综述。这篇综述强调了在个性化医疗、药物基因组学和人工智能的帮助下,药物发现和治疗技术是如何发展的。个性化医疗使治疗符合DNA模式,以获得更高的疗效和最小的副作用。药物基因组学根据基因差异预测药物的作用。人工智能加速了药物发现,提高了发现和评估药物线索的有效性和准确性。研究表明,定制的药物可以根据个体患者的个体遗传特征进行治疗,从而产生更好的治疗效果。药物基因组学通过考虑遗传变异促进精确的药物选择,减少不良反应。人工智能通过应用预测建模和数据驱动的评估来推动优化的药物开发途径,从而加速药物发现。总之,这些进步使跨医学学科的治疗实践更加有效和安全。药理学、基因组学和人工智能的结合,通过个性化治疗、提高药物安全性和治疗效果,正在彻底改变当代医疗保健。未来的研究应该是优化这些技术,克服伦理和监管问题,以促进更广泛的临床应用。
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来源期刊
CiteScore
6.40
自引率
2.60%
发文量
104
审稿时长
6-12 weeks
期刊介绍: Drug Development Research focuses on research topics related to the discovery and development of new therapeutic entities. The journal publishes original research articles on medicinal chemistry, pharmacology, biotechnology and biopharmaceuticals, toxicology, and drug delivery, formulation, and pharmacokinetics. The journal welcomes manuscripts on new compounds and technologies in all areas focused on human therapeutics, as well as global management, health care policy, and regulatory issues involving the drug discovery and development process. In addition to full-length articles, Drug Development Research publishes Brief Reports on important and timely new research findings, as well as in-depth review articles. The journal also features periodic special thematic issues devoted to specific compound classes, new technologies, and broad aspects of drug discovery and development.
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