Bioaccessibility assessment of Mn, Cu, Fe, and Cd in Henan Province wheat using physiologically based extraction

IF 2.9 4区环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES

Environmental Monitoring and Assessment Pub Date : 2025-04-26 DOI:10.1007/s10661-025-14049-8

Li Ma, Xuejin Zhao, Guobing Lin, Honghao Shi, Ziqi Li, Lianfeng Shen

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引用次数: 0

Abstract

As an important crop in China, wheat serves as a crucial source of micronutrients and a potential vector for toxic elements in human diets. This study systematically collected wheat grains from 54 counties in Henan Province and conducted in vitro physiological extraction experiments to assess the bioavailability of Mn, Cu, Fe, and Cd in wheat samples. Results turned out that the bioavailability of Cd significantly decreased from the gastric to the intestinal stage. The bioavailability of Mn exhibited similar trends to Cd in the two phases, whereas Cu and Fe showed a higher bioaccessibility in the intestinal phase compared to the gastric phase. Correlation analysis revealed that higher total metal concentrations always resulted in a higher bioaccessible fraction, and the bioaccessibility of Cd was positively correlated with Mn and its bioaccessibility. Eventually, health risk to Cd from wheat consumption evaluated by Monte Carlo simulation indicated that children exhibited a heightened vulnerability to health risks in comparison to adults and risks could be decreased significantly by introducing bioaccessibility. Consequently, it is evident that refining the relationship between bioaccessibility and biotoxicity of elements could provide the methodology to accurately and efficiently assess human health risks.

查看原文本刊更多论文

利用生理提取法评价河南省小麦中锰、铜、铁和镉的生物可及性

小麦是中国重要的农作物，是微量营养素的重要来源，也是人类饮食中有毒元素的潜在载体。本研究系统采集河南省54个县的小麦籽粒，进行体外生理提取实验，评估小麦样品中Mn、Cu、Fe和Cd的生物利用度。结果表明，从胃期到肠期，Cd的生物利用度显著降低。锰和镉在两个阶段的生物利用度趋势相似，而铜和铁在肠期的生物利用度高于胃期。相关性分析表明，总金属浓度越高，土壤的生物可及性越高，镉的生物可及性与锰及其生物可及性呈正相关。最后，通过蒙特卡罗模拟评估的小麦消费对镉的健康风险表明，与成人相比，儿童对健康风险的脆弱性更高，通过引入生物可及性可以显著降低风险。因此，明确元素的生物可及性与生物毒性之间的关系可以为准确有效地评估人类健康风险提供方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Environmental Monitoring and Assessment 环境科学-环境科学

CiteScore

4.70

自引率

6.70%

发文量

1000

审稿时长

7.3 months

期刊介绍： Environmental Monitoring and Assessment emphasizes technical developments and data arising from environmental monitoring and assessment, the use of scientific principles in the design of monitoring systems at the local, regional and global scales, and the use of monitoring data in assessing the consequences of natural resource management actions and pollution risks to man and the environment.