Efficacy of Punch Excision Combined With Superficial X-Ray for the Treatment of Keloids: A Single-Center Retrospective Study

IF 3.7 4区医学 Q1 DERMATOLOGY

Dermatologic Therapy Pub Date : 2025-04-22 DOI:10.1155/dth/4327219

Junyou Zheng, Fang Fang, Wenbo Bu

{"title":"Efficacy of Punch Excision Combined With Superficial X-Ray for the Treatment of Keloids: A Single-Center Retrospective Study","authors":"Junyou Zheng, Fang Fang, Wenbo Bu","doi":"10.1155/dth/4327219","DOIUrl":null,"url":null,"abstract":"<div>\n Background: Keloid management remains a challenge for clinicians. Recently, punch excision and photoelectric technology have demonstrated promising clinical applications for managing keloids; however, few studies have examined the efficacy and safety of punch excision combined with superficial X-ray for treating keloids.\n Objective: To investigate the efficacy and safety of punch excision combined with superficial X-ray for treating keloid.\n Methods: In this retrospective study, we analyzed the clinical records of 60 patients with keloid scars who underwent punch excision combined with superficial X-ray at our hospital, from April 2020 to April 2023. The Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS) 2.0 Patient Scale serve as the primary assessment tools to evaluate all patients, both prior to the initial treatment and one year after the completion of therapy. SPSS software was used for statistical analysis to assess keloid improvement.\n Results: In the 60 patients with keloids, varying degrees of improvement were observed. The VSS and POSAS scores recorded 1 year after treatment were significantly lower than the pretreatment scores (p < 0.001). No severe adverse reactions were observed during treatment.\n Conclusion: The combination of punch excision and superficial X-ray demonstrated a notable therapeutic effect on keloids without evident adverse reactions, offering a safe and effective option for patients with keloids.\n Trial Registration: Chinese Registry of Clinical Trials: ChiCTR2400094289\n </div>","PeriodicalId":11045,"journal":{"name":"Dermatologic Therapy","volume":"2025 1","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/dth/4327219","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatologic Therapy","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1155/dth/4327219","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Keloid management remains a challenge for clinicians. Recently, punch excision and photoelectric technology have demonstrated promising clinical applications for managing keloids; however, few studies have examined the efficacy and safety of punch excision combined with superficial X-ray for treating keloids.

Objective: To investigate the efficacy and safety of punch excision combined with superficial X-ray for treating keloid.

Methods: In this retrospective study, we analyzed the clinical records of 60 patients with keloid scars who underwent punch excision combined with superficial X-ray at our hospital, from April 2020 to April 2023. The Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS) 2.0 Patient Scale serve as the primary assessment tools to evaluate all patients, both prior to the initial treatment and one year after the completion of therapy. SPSS software was used for statistical analysis to assess keloid improvement.

Results: In the 60 patients with keloids, varying degrees of improvement were observed. The VSS and POSAS scores recorded 1 year after treatment were significantly lower than the pretreatment scores (p < 0.001). No severe adverse reactions were observed during treatment.

Conclusion: The combination of punch excision and superficial X-ray demonstrated a notable therapeutic effect on keloids without evident adverse reactions, offering a safe and effective option for patients with keloids.

Trial Registration: Chinese Registry of Clinical Trials: ChiCTR2400094289

Abstract Image

查看原文本刊更多论文

穿孔切除联合浅表x线治疗瘢痕疙瘩的疗效：单中心回顾性研究

背景：瘢痕疙瘩的管理仍然是临床医生面临的挑战。最近，穿孔切除和光电技术在治疗瘢痕疙瘩方面表现出了良好的临床应用前景；然而，很少有研究考察打孔切除联合浅表x线治疗瘢痕疙瘩的有效性和安全性。目的：探讨穿孔切除联合浅表x线治疗瘢痕疙瘩的疗效和安全性。方法：回顾性分析2020年4月至2023年4月在我院行瘢痕疙瘩打孔切除联合浅表x线检查的60例瘢痕疙瘩患者的临床资料。温哥华疤痕量表（VSS）和患者和观察者疤痕评估量表（POSAS） 2.0患者量表作为评估所有患者的主要评估工具，包括初始治疗前和治疗完成一年后。应用SPSS软件对瘢痕疙瘩改善情况进行统计分析。结果：60例瘢痕疙瘩患者均有不同程度的改善。治疗后1年的VSS和POSAS评分显著低于治疗前评分(p <；0.001)。治疗过程中未见严重不良反应。结论：打孔切除联合浅表x线治疗瘢痕疙瘩疗效显著，无明显不良反应，为瘢痕疙瘩患者提供了一种安全有效的治疗选择。试验注册：中国临床试验注册中心：ChiCTR2400094289

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Dermatologic Therapy 医学-皮肤病学

CiteScore

7.00

自引率

8.30%

发文量

711

审稿时长

3 months

期刊介绍： Dermatologic Therapy has been created to fill an important void in the dermatologic literature: the lack of a readily available source of up-to-date information on the treatment of specific cutaneous diseases and the practical application of specific treatment modalities. Each issue of the journal consists of a series of scholarly review articles written by leaders in dermatology in which they describe, in very specific terms, how they treat particular cutaneous diseases and how they use specific therapeutic agents. The information contained in each issue is so practical and detailed that the reader should be able to directly apply various treatment approaches to daily clinical situations. Because of the specific and practical nature of this publication, Dermatologic Therapy not only serves as a readily available resource for the day-to-day treatment of patients, but also as an evolving therapeutic textbook for the treatment of dermatologic diseases.