Surgical outcomes of the reinforced Ross procedure in the pediatric population

Markian M. Bojko MD, MPH, Neelesh Bagrodia BS, Luke Wiggins MD, Chace Mitchell MD, John D. Cleveland MD, David C. Cleveland MD, Vaughn A. Starnes MD
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引用次数: 0

Abstract

Objective

External reinforcement of the Ross autograft is well described in adults. However, this technique is poorly studied in pediatric patients, and indications are not strictly defined. We aim to describe our institutions experience with external Ross reinforcement in pediatric patients.

Methods

Between 2008 and 2023, 43 patients (≤18 years) underwent the Ross procedure with external Dacron graft reinforcement. Baseline characteristics, echocardiographic measurements, and postoperative outcomes were analyzed. The median [range] follow-up (years) was 2.01 [0.13-14.94] in children <13 years and 1.31 [0.05-11.57] in adolescents 13-18 years (P = .505).

Results

The median age [range] was 14 years [5-18], median weight was 56 kg [19-142], and the median body surface area was 1.6 m2 [0.7-2.2]. A total of 39 of 43 patients had aortic insufficiency (AI) or mixed stenosis with insufficiency, and 4 of 43 had stenosis alone. The median [range] preoperative pulmonary valve diameter was 2.1 cm [1.8-2.9] and the median [range] aortic valve annulus diameter was 2.4 cm [1.2-3.7]. The most common Dacron graft size was 26 mm. The operative mortality rate was 1 of 43 (2.3%), and there were 5 of 43 (12%) unplanned cardiac reoperations in the postoperative period. At 1 month postprocedure, the median [range] peak valve gradient was 16 mm Hg [2-35] and 2 patients had moderate AI with the remainder having mild or less AI. There was one patient who required late autograft reintervention at 10 years for autograft stenosis. The 5-year Kaplan-Meier survival was 97.7% (93.3%-100.0%).

Conclusions

With careful patient selection, external Ross reinforcement can be performed in the pediatric population and achieves acceptable postoperative valve hemodynamics, survival, and freedom from reintervention.
强化罗斯手术在儿科人群中的手术效果
目的罗斯自体移植物的外部加固在成人中有很好的报道。然而,这项技术在儿科患者中的研究很少,适应症也没有严格定义。我们的目的是描述我们的机构经验与外部罗斯强化儿科患者。方法2008年至2023年间,43例(≤18岁)患者接受了体外涤纶移植物加固的Ross手术。分析基线特征、超声心动图测量和术后结果。13岁儿童的中位随访(年)为2.01[0.13-14.94],13-18岁青少年的中位随访(年)为1.31 [0.05-11.57](P = 0.505)。结果中位年龄[范围]为14岁[5-18岁],中位体重为56 kg[19-142],中位体表面积为1.6 m2[0.7-2.2]。43例患者中有39例存在主动脉瓣不全(AI)或混合狭窄伴不全,43例患者中有4例存在单独狭窄。术前肺动脉瓣直径中位数[范围]为2.1 cm[1.8-2.9],主动脉瓣环直径中位数[范围]为2.4 cm[1.2-3.7]。最常见的涤纶接枝尺寸为26毫米。手术死亡率为1 / 43(2.3%),43例非计划心脏再手术中有5例(12%)。术后1个月,瓣膜峰值梯度中位数[范围]为16 mm Hg[2-35], 2例患者为中度AI,其余患者为轻度或轻度AI。有1例患者因自体移植物狭窄在10年时需要晚期自体移植物再干预。5年Kaplan-Meier生存率为97.7%(93.3% ~ 100.0%)。结论:通过谨慎的患者选择,外部罗斯加固可以在儿科人群中进行,并获得可接受的术后瓣膜血流动力学,生存和免于再干预。
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