Pulmonary hypertension and outcomes following left atrial appendage occlusion device placement for atrial fibrillation: A population-based analysis

IF 2.2 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Arrhythmia Pub Date : 2025-04-20 DOI:10.1002/joa3.70071

Nadhem Abdallah MD, Momen Alsayed MBBS

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Abstract

Background

Pulmonary hypertension (PH) is linked to poor outcomes in cardiac procedures, but data on left atrial appendage occlusion device (LAAOD) placement are limited.

Methods

Using the 2016–2020 Nationwide Readmission Database, we compared in-hospital outcomes between AF patients with and without PH.

Results

Among 48,692 AF-LAAOD patients, 5.9% had PH. PH was associated with higher mortality, prolonged ventilation, AKI, vasopressor use, interatrial septum repair, LOS, and costs. No differences were found in the odds of readmissions, major bleeding events, vascular complications, stroke, or cardiac arrest.

Conclusion

PH in AF-LAAOD patients is associated with higher fatal and nonfatal adverse outcomes.

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心房颤动左心房附件闭塞装置置入后肺动脉高压和预后：一项基于人群的分析

背景肺动脉高压（PH）与心脏手术的不良预后有关，但有关左心房阑尾闭塞器（LAAOD）置入的数据却很有限。方法我们利用 2016-2020 年全国再入院数据库，比较了有肺动脉高压和无肺动脉高压的房颤患者的院内预后。结果在 48692 名房颤-LAAOD 患者中，5.9% 有 PH。PH 与较高的死亡率、通气时间延长、AKI、血管加压、房间隔修复、住院时间和费用相关。在再入院、大出血事件、血管并发症、中风或心脏骤停的几率方面没有发现差异。结论房颤-LAAOD 患者的 PH 与较高的致命性和非致命性不良后果相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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