Detection and Separation of Paracetamol and p-Aminophenol Using Activated Glassy Carbon Electrodes

IF 2.7 4区化学 Q3 CHEMISTRY, PHYSICAL

Electrocatalysis Pub Date : 2025-02-19 DOI:10.1007/s12678-025-00941-x

Dereje Yenealem, Shimelis Admassie, Santhi Raju Pilli, Sowjanya Motana, Dessie Tibebe

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Abstract

The square wave voltammetry (SWV) method was utilized to simultaneously find paracetamol and p-aminophenol (PAP) by applying an activated glassy carbon electrode (AGCE). The results showed that the AGCE effectively facilitated the oxidation of both compounds, exhibiting a significant separation of their oxidation peaks by approximately 280.5 mV, which is sufficient for their concurrent detection. The linear ranges and detection limits were found to be 6.0 × 10⁻⁷–1.0 × 10⁻⁴ mol L⁻¹ and 1.0 × 10⁻⁶–8.0 × 10⁻⁴ mol L⁻¹; 1.39 × 10⁻⁸ mol L⁻¹ and 1.91 × 10⁻⁸ mol L⁻¹ for APAP and PAP, correspondingly. Ultimately, the adopted method was effectively implemented to measure APAP and PAP in commercial-grade tablets, yielding average recoveries of 103.1% for APAP and 101.0% for PAP.

Graphical Abstract

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使用活性玻璃碳电极检测和分离扑热息痛和对氨基苯酚

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来源期刊

Electrocatalysis CHEMISTRY, PHYSICAL-ELECTROCHEMISTRY

CiteScore

4.80

自引率

6.50%

发文量

审稿时长

>12 weeks

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