Sclerotherapy with polidocanol as a treatment for aneurysmal bone cyst: A systematic review

Q2 Medicine

Journal of Clinical Orthopaedics and Trauma Pub Date : 2025-04-04 DOI:10.1016/j.jcot.2025.103009

Yogi Prabowo, Anissa Feby Canintika, Randhi Maulana, Winona Andrari Mardhitiyani, Natan Kevin Partogu Siagian

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引用次数: 0

Abstract

Background

Sclerotherapy with polidocanol is a minimally invasive treatment for smaller Aneurysmal bone cysts (ABCs), offering safety and lower recurrence rates compared to surgery. Treatment choice depends on ABC size and location, with denosumab and titanium elastic nails as alternatives. To our knowledge, there are no systematic reviews regarding sclerotherapy with polidocanol as a treatment for ABCs. We aim to elucidate the effects of polidocanol in patients with ABCs.

Methods

This systematic review included studies involving patients with aneurysmal bone cyst treated with sclerotherapy using polidocanol as its agent. Literature search from database such as Pubmed, Cochrane, and Scopus resulted in 14 studies included in this review.

Results

Multiple studies have examined the effectiveness of percutaneous sclerotherapy with polidocanol as a primary treatment for ABCs. Most studies favored this approach without comparisons, while some compared it to extended curettage or other methods. Results varied, with some showing successful healing and pain relief, while others noted minor complications. Sequential polidocanol instillations were found to reduce cyst volume and minimize recurrence. Other interventions, like absolute alcohol gel and Denosumab, showed potential but with varying outcomes.

Conclusion

While percutaneous sclerotherapy with polidocanol has been prominently effective in managing aneurysmal bone cysts, further studies are required to identify the most effective and least invasive treatment strategies to optimize outcomes and minimize complications in clinical practice.

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多卡因醇硬化治疗动脉瘤性骨囊肿：系统综述

背景：与手术相比，聚多醇硬化治疗是一种治疗较小动脉瘤性骨囊肿（abc）的微创治疗方法，具有安全性和较低的复发率。治疗选择取决于ABC的大小和位置，可选择denosumab和钛弹性钉。据我们所知，目前还没有系统的综述关于用聚多卡因醇治疗abc的硬化疗法。我们的目的是阐明poly - canol对abc患者的影响。方法本系统综述纳入了以聚多坎醇为硬化剂治疗动脉瘤性骨囊肿患者的研究。从Pubmed、Cochrane和Scopus等数据库中检索文献，共纳入14项研究。结果：多项研究证实了经皮硬化治疗作为治疗abc的主要方法的有效性。大多数研究都赞成这种方法，但没有进行比较，而有些研究则将其与延长刮除或其他方法进行比较。结果各不相同，有些显示成功的愈合和疼痛缓解，而另一些显示轻微的并发症。序贯注射聚多坎醇可减少囊肿体积，减少复发。其他干预措施，如无水酒精凝胶和Denosumab，显示出潜力，但结果不同。结论经皮硬化治疗经皮多卡因醇治疗动脉瘤性骨囊肿疗效显著，但仍需进一步研究以确定最有效和微创的治疗策略，以优化临床效果并减少并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Orthopaedics and Trauma Medicine-Orthopedics and Sports Medicine

CiteScore

4.30

自引率

0.00%

发文量

181

审稿时长

92 days

期刊介绍： Journal of Clinical Orthopaedics and Trauma (JCOT) aims to provide its readers with the latest clinical and basic research, and informed opinions that shape today''s orthopedic practice, thereby providing an opportunity to practice evidence-based medicine. With contributions from leading clinicians and researchers around the world, we aim to be the premier journal providing an international perspective advancing knowledge of the musculoskeletal system. JCOT publishes content of value to both general orthopedic practitioners and specialists on all aspects of musculoskeletal research, diagnoses, and treatment. We accept following types of articles: • Original articles focusing on current clinical issues. • Review articles with learning value for professionals as well as students. • Research articles providing the latest in basic biological or engineering research on musculoskeletal diseases. • Regular columns by experts discussing issues affecting the field of orthopedics. • "Symposia" devoted to a single topic offering the general reader an overview of a field, but providing the specialist current in-depth information. • Video of any orthopedic surgery which is innovative and adds to present concepts. • Articles emphasizing or demonstrating a new clinical sign in the art of patient examination is also considered for publication. Contributions from anywhere in the world are welcome and considered on their merits.