Triarylmethyl Cations as Photocatalysts for Radical-Mediated Cycloaddition Reactions

IF 4.7 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-04-14 DOI:10.1021/acs.orglett.5c01103

Tomoya Hisada, Kazumichi Maeda, Yasuhiro Yamashita, Shu̅ Kobayashi

引用次数: 0

Abstract

We have developed a novel photocatalytic system using readily available triarylmethyl cations for radical-mediated (4 + 2) and (2 + 2) cycloaddition reactions. A variety of substituted triarylmethyl cations were investigated, and the optimal catalyst exhibited high efficiency and broad substrate scope, affording the desired cycloadducts in good to excellent yields with high regio- and diastereoselectivities. Furthermore, the catalyst could be immobilized on a polymer support and reused multiple times without a significant loss of activity.

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三芳基甲基阳离子在自由基介导的环加成反应中的光催化剂作用

我们已经开发了一种新的光催化系统，使用易于获得的三芳基甲基阳离子进行自由基介导的（4 + 2）和（2 + 2）环加成反应。对多种取代三芳基甲基阳离子进行了研究，优选出的催化剂效率高，底物范围广，能以较高的区域选择性和非对映选择性得到所需的环加合物。此外，该催化剂可以固定在聚合物载体上，并且可以多次重复使用，而不会有明显的活性损失。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.