Are Hospital Pharmacists Ready for Precision Medicine in Nigerian Healthcare? Insights From a Multi-Center Study

Health Care Science Pub Date : 2025-04-08 DOI:10.1002/hcs2.70008

Goodness C. Nwokebu, Shadrach C. Eze, Prince J. Meziem, Catherine C. Eleje, Emmanuel I. Ugwu, Manuella O. Dagogo-George, Favour O. Orisakwe, Gerald O. Ozota, Abdulmuminu Isah

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Abstract

Background

Precision medicine (PM) has taken center stage in healthcare since the completion of the genomic project. Developed countries have gradually integrated PM into mainstream patient management. However, Nigeria still grapples with wide acceptance, key translational research and implementation of PM. This study sought to explore the knowledge and attitude of PM among pharmacists as key stakeholders in the healthcare team.

Methods

A cross-sectional study was conducted in selected tertiary hospitals across the country. A 21-item semi-structured questionnaire was administered by hybrid online and physical methods and the results analyzed with Statistical Package for the Social Sciences Version 25. Descriptive statistics were used to summarize the data. A chi-square test was employed to determine the association of knowledge of PM and the sociodemographic characteristics of the study population.

Results

A total of 167 hospital pharmacists participated in the study. A high proportion of the participants are familiar with artificial intelligence (91.75%), Pharmacogenomics (84.5%), and precision medicine (61%). Overall, 38.9% of the pharmacists had a good knowledge while 13.2% had a poor knowledge of PM and associated terms. The level of knowledge did not correlate significantly with gender (X² = 3.21, p = 0.201), age (X² = 5, p = 0.27), marital status (X² = 3.21, p = 0.201), and professional level (X² = 6.85, p = 0.144). The most important value of precision medicine to hospital pharmacists is the ability to minimize the impact of disease through preventive medicine (49%) while a large portion are pursuing and or actively planning to pursue additional education in precision medicine.

Conclusions

There is a highly positive attitude toward the prospect of PM among hospital pharmacists in Nigeria. Education modules in this field are highly recommended as most do not have a holistic knowledge of terms used in PM. Also, more research aimed at translating PM knowledge into clinical practice is recommended.

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医院药剂师为尼日利亚医疗保健领域的精准医疗做好准备了吗？一项多中心研究的启示

背景自基因组计划完成以来，精准医疗（PM）已成为医疗保健领域的中心议题。发达国家已逐步将精准医疗纳入主流患者管理。然而，尼日利亚仍在努力实现精准医学的广泛接受、关键转化研究和实施。本研究旨在探讨作为医疗团队关键利益相关者的药剂师对 PM 的认识和态度。方法在全国选定的三级医院开展了一项横断面研究。通过在线和实体混合方法发放了一份 21 个项目的半结构式问卷，并使用社会科学统计软件包 25 版对结果进行了分析。使用描述性统计来总结数据。采用卡方检验确定可吸入颗粒物知识与研究人群社会人口学特征之间的关联。结果共有 167 名医院药剂师参与了研究。大部分参与者熟悉人工智能（91.75%）、药物基因组学（84.5%）和精准医疗（61%）。总体而言，38.9% 的药剂师对 PM 及相关术语有较好的了解，而 13.2% 的药剂师对 PM 及相关术语的了解较少。知识水平与性别（X2 = 3.21，p = 0.201）、年龄（X2 = 5，p = 0.27）、婚姻状况（X2 = 3.21，p = 0.201）和专业水平（X2 = 6.85，p = 0.144）无显著相关性。精准医学对医院药剂师最重要的价值是能够通过预防医学将疾病的影响降到最低（49%），而很大一部分药剂师正在或积极计划接受精准医学方面的进一步教育。结论尼日利亚医院药剂师对精准医学的前景持非常积极的态度。由于大多数人对 PM 中使用的术语缺乏全面了解，因此强烈建议在这一领域开展教育模块。此外，还建议开展更多旨在将 PM 知识转化为临床实践的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Health Care Science

CiteScore

0.90

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0.00%

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