Incidental Durotomy During Transforaminal Lumbar Interbody Fusion (TLIF) Surgery with Expandable Interbody Spacers: A Retrospective, Single-Center Analysis of Complications and Outcomes.
Linda Bättig, Francis Kissling, Stefan Motov, Felix C Stengel, Yesim Yildiz, Laurin Feuerstein, Gregor Fischer, Thomas Schöfl, Daniele Gianoli, Nader Hejrati, Benjamin Martens, Martin N Stienen, Lorenzo Bertulli
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引用次数: 0
Abstract
Study DesignRetrospective cohort study.ObjectivesTo evaluate the frequency, risk factors, and impact of incidental durotomy on adverse events and outcomes after TLIF with expandable interbody spacers.MethodsWe reviewed 433 consecutive patients treated by TLIF using expandable titanium interbody implants (ALTERA®, Globus Medical Inc) on 538 levels between December 2018 and September 2023. Patients with incidental durotomy (ID) and cerebrospinal fluid leakage were compared to patients without ID, focusing on patient-specific and surgery-related factors, adverse events, clinical outcomes (MacNab criteria), and radiological outcomes at discharge, 3, and 12 months.ResultsThe ID rate was 9.0% (39/433 patients). Patients with ID had lower BMI (26.1 ± 5.2 vs 28.0 ± 5.3 kg/m2, P = .03), longer surgery duration (358 ± 132 vs 305 ± 128 minutes, P = .01), and extended hospital stays (14.7 ± 12.8 vs 10.9 ± 8.2 days, P < .01). More postoperative adverse events (51.3% vs 28.7%, P = .004) with higher severity (28.2% vs 13.2% moderate to severe, P = .019) occurred at discharge. No differences were found in outcomes at 3 or 12 months. ID patients showed higher risks for impaired wound healing (adjusted OR, 4.39; 95% CI, 1.90-10.2; P = .001) and pulmonary embolism (adjusted OR, 3.52; 95% CI, 1.13-10.9; P = .029).ConclusionsIncidental durotomy was associated with longer surgery time, hospital stays, and increased early postoperative complications. While not affecting mid-to-long-term outcomes, ID increased risks for wound healing difficulties and pulmonary embolisms.
研究设计回顾性队列研究。目的评价附带硬膜切开术的频率、危险因素以及对可扩展椎间间隔器TLIF术后不良事件和预后的影响。方法:我们回顾了2018年12月至2023年9月期间连续433例使用可扩展钛体间植入物(ALTERA®,Globus Medical Inc .)在538个水平上接受TLIF治疗的患者。将偶发硬膜切开术(ID)和脑脊液漏的患者与未发生ID的患者进行比较,重点关注患者特异性和手术相关因素、不良事件、临床结局(MacNab标准)以及出院、3个月和12个月的放射学结局。结果确诊率为9.0%(39/433)。ID组患者BMI较低(26.1±5.2 vs 28.0±5.3 kg/m2, P = 0.03),手术时间较长(358±132 vs 305±128分钟,P = 0.01),住院时间较长(14.7±12.8 vs 10.9±8.2天,P < 0.01)。出院时发生的术后不良事件较多(51.3% vs 28.7%, P = 0.004),严重程度较高(28.2% vs 13.2%, P = 0.019)。3个月或12个月的结果没有发现差异。ID患者伤口愈合受损的风险更高(调整OR, 4.39;95% ci, 1.90-10.2;P = .001)和肺栓塞(校正OR, 3.52;95% ci, 1.13-10.9;P = .029)。结论偶发硬膜切开术手术时间长、住院时间长、术后早期并发症多。虽然不影响中长期预后,但内源性疾病增加了伤口愈合困难和肺栓塞的风险。
期刊介绍:
Global Spine Journal (GSJ) is the official scientific publication of AOSpine. A peer-reviewed, open access journal, devoted to the study and treatment of spinal disorders, including diagnosis, operative and non-operative treatment options, surgical techniques, and emerging research and clinical developments.GSJ is indexed in PubMedCentral, SCOPUS, and Emerging Sources Citation Index (ESCI).