Intraductal papillary neoplasm of the bile duct in the middle east: Case report

Khaled Demyati , Orabi Hajjeh , Amr Khaled , Usama Al Khuffash , Fathi Milhem , Ameer Awashra , Hanood Abu Rass
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Abstract

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare premalignant tumor characterized by papillary growth within the bile ducts, predominantly reported in East Asia. We present a 64-year-old male diagnosed with IPNB with focal stromal invasion, managed successfully with surgical resection. The case highlights unique endoscopic, imaging, and histopathological findings, and provides valuable data describing the unusual presentation of the case and the challenges faced in making the diagnosis. To our knowledge, this is the first reported case from the Middle East, emphasizing the rarity of IPNB in the region. This report underscores the importance of early diagnosis, proper imaging, and clear resection margins for optimal outcomes.
中东胆管导管内乳头状肿瘤1例
胆管内乳头状肿瘤(IPNB)是一种罕见的以胆管内乳头状生长为特征的癌前肿瘤,主要在东亚报道。我们报告一位64岁男性确诊为IPNB伴局灶性间质浸润,手术切除成功。该病例突出了独特的内窥镜、影像学和组织病理学发现,并提供了有价值的数据,描述了该病例的不寻常表现和做出诊断所面临的挑战。据我们所知,这是中东报告的首例病例,强调了IPNB在该地区的罕见性。本报告强调了早期诊断,正确的影像学检查和明确切除边缘的重要性,以获得最佳结果。
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