Magnetophoresis-Based particle separation in microfluidic channels using grooved current-carrying conductor: Design, simulation, and optimization

IF 2.5 3区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Journal of Magnetism and Magnetic Materials Pub Date : 2025-04-04 DOI:10.1016/j.jmmm.2025.173026

A. Nameni , M.H. Kayhani , V. Mashayekhi , M. Nazari

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Abstract

This study investigates the application of magnetophoresis for efficient particle separation within microfluidic channels. By modifying the structure of a current-carrying conductor, a controlled magnetic field gradient is generated. This gradient exerts precise forces on magnetic particles, influencing their trajectories in the laminar flow of the microchannel. The system design incorporates an asymmetric groove in the conductor to enhance the non-uniformity of the magnetic field, thereby optimizing particle manipulation. Finite element simulations are conducted to analyze and validate the performance of the system under varying parameters such as groove dimensions, electric current intensity, and fluid flow rates. Results demonstrate that optimal design parameters significantly improve separation efficiency, highlighting the potential of magnetophoresis for biomedical and industrial applications requiring precise particle handling in microfluidic environments.

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来源期刊

Journal of Magnetism and Magnetic Materials 物理-材料科学：综合

CiteScore

5.30

自引率

11.10%

发文量

1149

审稿时长

59 days

期刊介绍： The Journal of Magnetism and Magnetic Materials provides an important forum for the disclosure and discussion of original contributions covering the whole spectrum of topics, from basic magnetism to the technology and applications of magnetic materials. The journal encourages greater interaction between the basic and applied sub-disciplines of magnetism with comprehensive review articles, in addition to full-length contributions. In addition, other categories of contributions are welcome, including Critical Focused issues, Current Perspectives and Outreach to the General Public. Main Categories: Full-length articles: Technically original research documents that report results of value to the communities that comprise the journal audience. The link between chemical, structural and microstructural properties on the one hand and magnetic properties on the other hand are encouraged. In addition to general topics covering all areas of magnetism and magnetic materials, the full-length articles also include three sub-sections, focusing on Nanomagnetism, Spintronics and Applications. The sub-section on Nanomagnetism contains articles on magnetic nanoparticles, nanowires, thin films, 2D materials and other nanoscale magnetic materials and their applications. The sub-section on Spintronics contains articles on magnetoresistance, magnetoimpedance, magneto-optical phenomena, Micro-Electro-Mechanical Systems (MEMS), and other topics related to spin current control and magneto-transport phenomena. The sub-section on Applications display papers that focus on applications of magnetic materials. The applications need to show a connection to magnetism. Review articles: Review articles organize, clarify, and summarize existing major works in the areas covered by the Journal and provide comprehensive citations to the full spectrum of relevant literature.