Correction to “Synthesis of Cationic Cyclic Oligo(disulfide)s via Cyclo-Depolymerization: A Redox-Responsive and Potent Antibacterial Reagent”

Abstract

In the original publication, the H&E staining image for the Rifampicin group in Figure 8E was incorrectly duplicated as the CCO2-64% group. The corrected Figure 8E below now accurately displays the H&E staining of the Rifampicin group. The conclusions remain valid since the wound analysis relied on the complete data set in Figure S64. Figure 8. In vivo antimicrobial activity study of CCOs in the murine full-thickness wound infection model (n = 4 mice for each group, two wounds in each mouse). (A) Schematic diagram of the full-thickness wound infection model induced by S. aureus. The treatment groups were CCO1, CCO2-64%, rifampicin (positive control), and saline (negative control). (B) Bacterial loading in the wound treated with 20 μL of different solutions (400 × MIC of CCO1, 400 × MIC of CCO2-64%, 400 × MIC of rifampicin, and saline, respectively) and n = 6 wounds per group. All statistical significance as determined by the two-tailed t-test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. (C) Changes in wound sizes in the wound infection model after being treated with CCO1, CCO2-64%, rifampicin, and saline at 0, 1, 3, 5, and 7 days (n = 8 wounds per group). (D) Digital images of bacterium-infected mice skin wounds with different treatments. (E) Representative wound histological analysis after treatment for 7 days by H&E staining and Masson staining in the wound infection model. The scale bar is 100 μm. This article has not yet been cited by other publications.