"Survey on the burden, epidemiological and clinical characteristics of snakebite envenoming in the Health Demographic Surveillance System (HDSS) of Taabo (Southern Côte d'Ivoire)".

IF 3.4 2区医学 Q1 PARASITOLOGY

PLoS Neglected Tropical Diseases Pub Date : 2025-04-07 DOI:10.1371/journal.pntd.0012983

Tanoh Amany Serge Raymond N'Krumah, Bognan Valentin Koné, Yao Didier Koffi, Dognimin Ismael Coulibaly, Abdoulaye Tall, Siaka Koné, Simone Toppino, Marija Stojkovic, Bassirou Bonfoh, Thomas Junghanss

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引用次数: 0

Abstract

Background: In Sub-Saharan Africa, reliable data on the burden, clinical epidemiology and management of snakebites remains scarce. Mostly, crude population and institution-based estimates have been reported. The aim of this study was to estimate the burden and describe the epidemiological and clinical characteristics of snakebite envenoming based on population- (HDSS) data.

Methods: A cross-sectional snakebite survey was conducted in all households in the Ahondo Health Area (AHA), a sub-population of the Taabo Health and Demographic Surveillance System (HDSS) between October 2 to December 22, 2023. All household members were interviewed, and a questionnaire was administered to snakebite cases. Epidemiological and clinical characteristics were described, and the annual snakebite incidence calculated.

Results: 795 households were surveyed, representing 3,924 people in the AHA. The annual incidence of snakebites per 100,000 population was 280.3 (CI: 140.0 - 501.0), the case-fatality rate 2.0% (95%CI: 0.04 - 10.5) and the median age of snakebite victims 43 years. The annual incidence of snakebites was significantly higher in the seasonally used agricultural camps (3296.7 cases per 100,000 inhabitants) than in the villages (208.7 cases per 100,000 inhabitants). Snakebites most frequently occurred in the morning and at night. Patients employed dangerous "first aid" measures. Most snakebite victims were treated by traditional healers. None of the cases attending the health services received antivenoms.

Conclusion: Snakebite envenoming remains a threat for rural communities at an unacceptable high level unchanged since the second half of the last century. Reliable community-based data on the incidence, circumstances and management of snakebite envenoming is only the first step to mitigate the neglected health problem. Implementation of prevention measures, first aid and clinical management, including access to antivenoms, must immediately follow.

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“塔博（Côte科特迪瓦南部）卫生人口监测系统（HDSS）中蛇咬伤的负担、流行病学和临床特征调查”。

背景：在撒哈拉以南非洲，关于蛇咬伤的负担、临床流行病学和管理的可靠数据仍然很少。报告的大多是粗略的人口和基于机构的估计。本研究的目的是根据人口（HDSS）数据估计蛇咬伤的负担，并描述蛇咬伤的流行病学和临床特征。方法：于2023年10月2日至12月22日对Taabo健康与人口监测系统（HDSS）亚群Ahondo卫生区（AHA）的所有家庭进行了横断面蛇咬调查。对所有家庭成员进行了访谈，并对蛇咬伤病例进行了问卷调查。描述流行病学和临床特征，计算年蛇咬伤发生率。结果：调查了795个家庭，代表了美国心脏协会的3924人。年每10万人毒蛇咬伤发生率为280.3例（CI: 140.0 ~ 501.0），病死率为2.0% (95%CI: 0.04 ~ 10.5)，毒蛇咬伤受害者的中位年龄为43岁。季节性农业营地的年蛇咬伤发生率（每10万居民3296.7例）显著高于村庄（每10万居民208.7例）。蛇咬伤最常发生在早晨和晚上。病人采取了危险的“急救”措施。大多数被蛇咬伤的人都是由传统治疗师治疗的。到保健服务部门就诊的病例无一人获得抗蛇毒血清。结论：自上世纪下半叶以来，蛇咬伤事件对农村社区的威胁仍处于不可接受的高水平。关于蛇咬伤的发生率、情况和管理的可靠社区数据只是减轻被忽视的健康问题的第一步。必须立即实施预防措施、急救和临床管理，包括获得抗蛇毒血清。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PLoS Neglected Tropical Diseases PARASITOLOGY-TROPICAL MEDICINE

自引率

10.50%

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723

期刊介绍： PLOS Neglected Tropical Diseases publishes research devoted to the pathology, epidemiology, prevention, treatment and control of the neglected tropical diseases (NTDs), as well as relevant public policy. The NTDs are defined as a group of poverty-promoting chronic infectious diseases, which primarily occur in rural areas and poor urban areas of low-income and middle-income countries. Their impact on child health and development, pregnancy, and worker productivity, as well as their stigmatizing features limit economic stability. All aspects of these diseases are considered, including: Pathogenesis Clinical features Pharmacology and treatment Diagnosis Epidemiology Vector biology Vaccinology and prevention Demographic, ecological and social determinants Public health and policy aspects (including cost-effectiveness analyses).